KEGG   DRUG: Aprinocarsen sodium
Entry
D02970                      Drug                                   
Name
Aprinocarsen sodium (USAN);
Affinitak (TN)
Formula
C196H230N68O105P19S19. 19Na
Exact mass
6848.2513
Mol weight
6852.90
Efficacy
Antineoplastic, Protein kinase C-alpha inhibitor
  Type
Antisense oligonucleotide
Comment
Treatment of non-small cell lung cancer
Target
PRKCA [HSA:5578] [KO:K02677] (mRNA)
  Pathway
hsa04010  MAPK signaling pathway
hsa04014  Ras signaling pathway
hsa05200  Pathways in cancer
Brite
Target-based classification of drugs [BR:br08310]
 Protein kinases
  Serine/threonine kinases
   AGC group
    PRKCA
     D02970  Aprinocarsen sodium (USAN)
Other DBs
CAS: 331257-53-5
PubChem: 17397127
LinkDB

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