| Entry |
|
|---|
| Name |
Besonprodil (USAN) |
|---|
| Formula |
C21H23FN2O3S
|
|---|
| Exact mass |
402.1413
|
|---|
| Mol weight |
402.48
|
|---|
| Structure |
|
|---|
| Class |
Neuropsychiatric agent
DG01498 NMDA receptor antagonist
|
|---|
| Efficacy |
Antiparkinsonian, NMDA 2B receptor antagonist |
|---|
| Comment |
Treatment of Parkinson's disease
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07235 | N-Methyl-D-aspartic acid (NMDA) receptor antagonists |
|
|---|
| Brite |
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01498 NMDA receptor antagonist
D03100 Besonprodil
Target-based classification of drugs [BR:br08310]
Ion channels
Ligand-gated ion channels
Glutamate (ionotropic), NMDA
GRIN2B (NMDAR2B)
D03100 Besonprodil (USAN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 28
1 C8x C 30.7300 -14.6300
2 C8y C 30.7300 -16.0300
3 C8x C 31.9900 -16.7300
4 C8y C 33.2500 -16.0300
5 C8y C 33.2500 -14.6300
6 C8x C 31.9900 -13.8600
7 O7x O 34.5800 -16.4500
8 C8y C 35.3500 -15.3300
9 N4x N 34.5800 -14.1400
10 O6a O 36.7500 -15.3300
11 S4a S 29.5400 -16.6600
12 C1b C 28.3500 -16.0300
13 O3c O 29.5400 -18.1300
14 C1b C 27.1600 -16.6600
15 N1y N 25.9700 -16.0300
16 C1x C 24.7800 -16.6600
17 C1x C 23.5900 -15.9600
18 C1y C 23.5900 -14.5600
19 C1x C 24.7800 -13.8600
20 C1x C 25.9700 -14.5600
21 C1b C 22.3300 -13.8600
22 C8y C 21.1400 -14.5600
23 C8x C 21.1400 -16.0300
24 C8x C 19.8800 -16.6600
25 C8y C 18.6900 -15.9600
26 C8x C 18.6900 -14.5600
27 C8x C 19.8800 -13.8600
28 X F 17.5000 -16.6600
BOND 31
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 7 8 1
9 8 9 1
10 5 9 1
11 8 10 2
12 2 11 1
13 11 12 1
14 11 13 2
15 12 14 1
16 14 15 1
17 15 16 1
18 16 17 1
19 17 18 1
20 18 19 1
21 19 20 1
22 15 20 1
23 18 21 1
24 21 22 1
25 22 23 2
26 23 24 1
27 24 25 2
28 25 26 1
29 26 27 2
30 22 27 1
31 25 28 1
|
|---|
