| Entry |
|
|---|
| Name |
Bromodiphenhydramine hydrochloride (USP);
Bromazine hydrochloride;
Bromanyl (TN) |
|---|
| Formula |
C17H21BrNO. Cl
|
|---|
| Exact mass |
369.0495
|
|---|
| Mol weight |
370.71
|
|---|
| Structure |
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|---|
| Simcomp |
|
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| Class |
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
|
|---|
| Remark |
|
|---|
| Efficacy |
Antiallergic, H1 receptor antagonist |
|---|
| Comment |
Bromodiphenhydramine is called Bromazine in INN.
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04750 | Inflammatory mediator regulation of TRP channels |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07212 | Histamine H1 receptor antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
R RESPIRATORY SYSTEM
R06 ANTIHISTAMINES FOR SYSTEMIC USE
R06A ANTIHISTAMINES FOR SYSTEMIC USE
R06AA Aminoalkyl ethers
R06AA01 Bromazine
D03166 Bromodiphenhydramine hydrochloride (USP)
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
D03166 Bromodiphenhydramine hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Histamine
HRH1
D03166 Bromodiphenhydramine hydrochloride (USP)
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 21
1 C8x C 18.9000 -33.7400
2 C8y C 18.9000 -35.1400
3 C8x C 20.1124 -35.8400
4 C8x C 21.3249 -35.1400
5 C8y C 21.3249 -33.7400
6 C8x C 20.1124 -33.0400
7 C1c C 22.5560 -33.0290
8 C8y C 23.7612 -33.7247
9 C8x C 23.7616 -35.1396
10 C8x C 24.9742 -35.8393
11 C8x C 26.1865 -35.1389
12 C8x C 26.1860 -33.7239
13 C8x C 24.9734 -33.0243
14 O2a O 22.5557 -31.6401
15 X Br 17.6876 -35.8400
16 C1b C 23.7562 -30.9466
17 C1b C 24.9462 -31.6335
18 N1c N 26.1360 -30.9462 #+
19 C1a C 27.3263 -31.6332
20 C1a C 26.1359 -29.5402
21 X Cl 29.7500 -34.5800 #-
BOND 21
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 5 7 1
8 7 8 1
9 8 9 2
10 9 10 1
11 10 11 2
12 11 12 1
13 12 13 2
14 8 13 1
15 7 14 1
16 2 15 1
17 14 16 1
18 16 17 1
19 17 18 1
20 18 19 1
21 18 20 1
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