KEGG   DRUG: ClorgilineHelp
Entry
D03248                      Drug                                   

Name
Clorgiline (INN);
Clorgyline
Formula
C13H15Cl2NO
Exact mass
271.0531
Mol weight
272.1703
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Neuropsychiatric agent
 DG01568  MAO inhibitor
  DG01558  Monoamine oxidase A inhibitor
Remark
Same as: C11685
Efficacy
Antidepressant, Monoamine oxidase A (MAO-A) inhibitor
Target
MAOA [HSA:4128] [KO:K00274]
  Pathway
hsa00260  Glycine, serine and threonine metabolism
hsa00330  Arginine and proline metabolism
hsa00340  Histidine metabolism
hsa00350  Tyrosine metabolism
hsa00360  Phenylalanine metabolism
hsa00380  Tryptophan metabolism
hsa00982  Drug metabolism - cytochrome P450
hsa04726  Serotonergic synapse
hsa04728  Dopaminergic synapse
Interaction
Drug interaction
Structure map
map07216  Catecholamine transferase inhibitors
Brite
Target-based classification of drugs [BR:br08310]
 Enzymes
  Oxidoreductases (EC1)
   Amine oxidases
    MAOA
     D03248  Clorgiline (INN)
BRITE hierarchy
Other DBs
CAS: 17780-72-2
PubChem: 17397401
ChEBI: 3763
ChEMBL: CHEMBL8706
PDB-CCD: MLG[PDBj]
LigandBox: D03248
NIKKAJI: J10.191E
LinkDB All DBs
KCF data Show

ATOM        17
            1   C1b C    25.5302  -19.1297
            2   N1c N    25.5302  -20.5361
            3   C1b C    26.7382  -21.2247
            4   C1a C    24.3163  -21.2306
            5   C3b C    27.9519  -20.5244
            6   C3a C    29.1162  -19.7510
            7   C1b C    24.3251  -18.4176
            8   C8y C    20.6990  -19.1072
            9   O2a O    21.9070  -18.4129
            10  C8x C    20.6990  -20.5135
            11  C8y C    19.4853  -18.4070
            12  C8x C    19.4853  -21.2138
            13  C8x C    18.2656  -19.1072
            14  C8y C    18.2656  -20.5135
            15  C1b C    23.1146  -19.1133
            16  X   Cl   19.4866  -17.0108
            17  X   Cl   17.0573  -21.2131
BOND        17
            1     2   4 1
            2     3   5 1
            3     5   6 3
            4     8   9 1
            5     8  10 1
            6     8  11 2
            7    10  12 2
            8    11  13 1
            9    12  14 1
            10   13  14 2
            11    7   1 1
            12    9  15 1
            13   15   7 1
            14    1   2 1
            15   11  16 1
            16    2   3 1
            17   14  17 1

» Japanese version   » Back

DBGET integrated database retrieval system