| Entry |
|
|---|
| Name |
Capromorelin tartrate (USAN) |
|---|
| Formula |
C28H35N5O4. C4H6O6
|
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| Exact mass |
655.2853
|
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| Mol weight |
655.69
|
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| Structure |
|
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| Efficacy |
Growth hormone secretagogue receptor (GHSR) agonist |
|---|
| Comment |
growth hormone release-stimulating peptide
Treatment and prevention of frailty, treatment of congestive heart failure, treatment of catabolic illness
|
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| Target |
|
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Brite |
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Ghrelin
GHSR
D03373 Capromorelin tartrate (USAN)
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 47
1 C1c C 21.0337 -15.5246
2 C5a C 22.2190 -14.8272
3 N1b N 19.8484 -14.8272
4 N1y N 23.4043 -15.5246
5 O5a O 22.2190 -13.5025
6 C5a C 18.6630 -15.5246
7 C1x C 24.5897 -14.8272
8 C1x C 23.4043 -16.9191
9 C1d C 17.4776 -14.8272
10 C1z C 25.7751 -15.5246
11 C1x C 24.5897 -17.6163
12 N1a N 16.2923 -15.5246
13 C2y C 25.7751 -16.9191
14 N2x N 27.0999 -17.2677
15 N1y N 27.8668 -16.1520
16 C5x C 26.9604 -15.0364
17 C1a C 29.2614 -16.1520
18 O5x O 27.3090 -13.7814
19 C1b C 21.0337 -16.9191
20 O2a O 19.7786 -17.6163
21 C1b C 19.7786 -19.0109
22 C8y C 18.6630 -19.7081
23 C8x C 17.4776 -19.0109
24 C8x C 16.2923 -19.7081
25 C8x C 16.2923 -21.1026
26 C8x C 17.4080 -21.7302
27 C8x C 18.6630 -21.0329
28 C1b C 25.7751 -13.0144
29 C8y C 24.5897 -12.3171
30 C8x C 24.5897 -10.9226
31 C8x C 23.4043 -10.2951
32 C8x C 22.1493 -10.9226
33 C8x C 22.1493 -12.3171
34 C8x C 23.4043 -13.0144
35 O5a O 18.6630 -16.9191
36 C1a C 17.4776 -13.5025
37 C1a C 16.2923 -14.1998
38 O6a O 22.6507 -19.9892
39 C6a C 23.8610 -20.6880
40 C1c C 25.0713 -19.9892
41 C1c C 26.2815 -20.6880
42 C6a C 27.4920 -19.9892
43 O6a O 28.7022 -20.6880
44 O6a O 23.8610 -22.0854
45 O1a O 25.0713 -18.5917
46 O1a O 26.2815 -22.0855
47 O6a O 27.4920 -18.5920
BOND 49
1 1 2 1
2 1 3 1
3 2 4 1
4 2 5 2
5 3 6 1
6 4 7 1
7 4 8 1
8 6 9 1
9 7 10 1
10 8 11 1
11 9 12 1
12 10 13 1
13 11 13 1
14 13 14 2
15 14 15 1
16 15 16 1
17 16 10 1
18 15 17 1
19 16 18 2
20 1 19 1 #Up
21 19 20 1
22 20 21 1
23 21 22 1
24 22 23 2
25 23 24 1
26 24 25 2
27 25 26 1
28 26 27 2
29 22 27 1
30 10 28 1 #Down
31 28 29 1
32 29 30 2
33 30 31 1
34 31 32 2
35 32 33 1
36 33 34 2
37 29 34 1
38 6 35 2
39 9 36 1
40 9 37 1
41 38 39 1
42 39 40 1
43 40 41 1
44 41 42 1
45 42 43 1
46 39 44 2
47 40 45 1 #Down
48 41 46 1 #Down
49 42 47 2
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