| Entry |
|
|---|
| Name |
Cefuroxime pivoxetil (USAN) |
|---|
| Formula |
C23H28N4O11S
|
|---|
| Exact mass |
568.1475
|
|---|
| Mol weight |
568.56
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
|
|---|
| Remark |
| Product (DG00558): | D00914<JP/US> D00915<US> |
|
|---|
| Efficacy |
Antibacterial, Cell wall biosynthesis inhibitor |
|---|
| Comment |
Active form of prodrug: Cefuroxime [DR: D00262]
|
|---|
| Target |
penicillin binding protein |
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01D OTHER BETA-LACTAM ANTIBACTERIALS
J01DC Second-generation cephalosporins
J01DC02 Cefuroxime
D03431 Cefuroxime pivoxetil (USAN)
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01A ANTIINFECTIVES
S01AA Antibiotics
S01AA27 Cefuroxime
D03431 Cefuroxime pivoxetil (USAN)
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01714 Cephalosporin skeleton group
DG01488 Cephem
DG00558 Cefuroxime
D03431 Cefuroxime pivoxetil
DG01775 Second-generation cephalosporin
DG00558 Cefuroxime
D03431 Cefuroxime pivoxetil
DG01804 Oxyimino beta-lactam
DG00558 Cefuroxime
D03431 Cefuroxime pivoxetil
Antimicrobials [BR:br08307]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
Second-generation cephalosporin
D03431 Cefuroxime pivoxetil (USAN)
Prodrugs [br08324.html]
D03431
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01714 Cephalosporin skeleton group
DG01488 Cephem
DG00558 Cefuroxime
DG01775 Second-generation cephalosporin
DG00558 Cefuroxime
DG01804 Oxyimino beta-lactam
DG00558 Cefuroxime
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
Second-generation cephalosporin
DG00558 Cefuroxime
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 39
1 C1y C 32.5159 -16.7317
2 N1y N 32.5159 -18.1006
3 C2y C 33.7017 -18.7850
4 C2y C 34.8871 -18.1006
5 C1x C 34.8871 -16.7317
6 S2x S 33.7017 -16.0472
7 C1y C 31.1469 -16.7317
8 C5x C 31.1469 -18.1006
9 N1b N 29.9615 -16.0472
10 C5a C 28.7759 -16.7317
11 O5a O 28.7759 -18.1006
12 O5x O 29.9615 -18.7850
13 C2c C 27.5903 -16.0472
14 C1b C 36.0907 -18.7959
15 C7a C 33.7017 -21.1833
16 O7a O 32.4994 -21.8775
17 O6a O 34.8705 -21.8583
18 C8y C 26.3858 -16.7431
19 O2x O 25.2563 -15.9478
20 C8x C 24.1464 -16.7765
21 C8x C 24.5914 -18.0881
22 C8x C 25.9764 -18.1403
23 N2b N 27.5902 -14.6574
24 O7a O 37.2931 -18.1023
25 C7a C 38.4552 -18.7738
26 N1a N 39.6253 -18.0985
27 O6a O 38.4548 -20.1496
28 C1c C 31.3212 -21.1969
29 O7a O 30.1666 -21.8633
30 C7a C 28.9936 -21.1857
31 C1d C 27.8294 -21.8575
32 C1a C 31.3209 -19.8036
33 O6a O 28.9938 -19.8035
34 C1a C 26.6186 -22.5566
35 O2a O 27.1414 -20.6660
36 C1a C 28.5396 -23.0875
37 C1a C 25.7323 -20.6658
38 O2a O 28.8066 -13.9551
39 C1a C 28.8066 -12.5551
BOND 41
1 1 2 1
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 1
6 1 6 1
7 1 7 1
8 7 8 1
9 2 8 1
10 7 9 1 #Up
11 9 10 1
12 10 11 2
13 8 12 2
14 10 13 1
15 4 14 1
16 3 15 1
17 15 16 1
18 15 17 2
19 13 18 1
20 18 19 1
21 19 20 1
22 20 21 2
23 21 22 1
24 18 22 2
25 13 23 2
26 14 24 1
27 24 25 1
28 25 26 1
29 25 27 2
30 16 28 1
31 28 29 1
32 29 30 1
33 30 31 1
34 28 32 1
35 30 33 2
36 31 34 1
37 31 35 1
38 31 36 1
39 35 37 1
40 23 38 1
41 38 39 1
|
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