KEGG   DRUG: CloprednolHelp
Entry
D03561                      Drug                                   

Name
Cloprednol (USAN/INN);
Cloradryn (TN)
Formula
C21H25ClO5
Exact mass
392.1391
Mol weight
392.8732
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Anti-inflammatory
 DG01955  Corticosteroid
  DG02068  Glucocorticoid
Remark
ATC code: H02AB14
Efficacy
Antiasthmatic, Glucocorticoid receptor agonist
Target
NR3C1 (GR) [HSA:2908] [KO:K05771]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
  H02 CORTICOSTEROIDS FOR SYSTEMIC USE
   H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
    H02AB Glucocorticoids
     H02AB14 Cloprednol
      D03561  Cloprednol (USAN/INN)
Target-based classification of drugs [BR:br08310]
 Nuclear receptors
  Estrogen like receptors
   3-Ketosteroid receptor
    NR3C1 (GR)
     D03561  Cloprednol (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 5251-34-3
PubChem: 17397681
ChEMBL: CHEMBL1697832
LigandBox: D03561
NIKKAJI: J8.826I
LinkDB All DBs
KCF data Show

ATOM        27
            1   C1z C    26.5612  -17.3125
            2   C1z C    25.3973  -17.9686
            3   C1x C    27.7138  -17.9858
            4   C5a C    26.5498  -15.5323
            5   C1y C    25.3914  -19.3096
            6   C1x C    24.2506  -17.2954
            7   C1a C    25.3803  -16.6279
            8   C1x C    27.7082  -19.3210
            9   C1y C    24.2277  -19.9772
            10  C1y C    23.0809  -17.9516
            11  C1y C    23.0696  -19.2923
            12  C2x C    24.2277  -21.3181
            13  C1z C    21.9054  -19.9657
            14  C2y C    23.0581  -21.9913
            15  C2y C    21.8998  -21.3066
            16  C2x C    20.7475  -19.2868
            17  C1a C    21.8943  -18.6192
            18  C2x C    20.7475  -21.9855
            19  C2x C    19.5777  -19.9657
            20  C5x C    19.5777  -21.3066
            21  X   Cl   23.0496  -23.3780
            22  O5x O    18.3948  -21.9879
            23  O1a O    21.8315  -17.2130
            24  O1a O    27.8005  -16.5963
            25  O5a O    25.2953  -14.8190
            26  C1b C    27.7540  -14.8262
            27  O1a O    28.9509  -15.5070
BOND        30
            1     1   2 1
            2     1   3 1
            3     1   4 1 #Up
            4     2   5 1
            5     2   6 1
            6     2   7 1 #Up
            7     3   8 1
            8     5   9 1
            9     6  10 1
            10    9  11 1
            11    9  12 1
            12   11  13 1
            13   12  14 2
            14   13  15 1
            15   13  16 1
            16   13  17 1 #Up
            17   15  18 2
            18   16  19 2
            19   18  20 1
            20    5   8 1
            21   10  11 1
            22   14  15 1
            23   19  20 1
            24   14  21 1
            25   20  22 2 #Up
            26   10  23 1 #Up
            27    1  24 1 #Down
            28    4  25 2
            29    4  26 1
            30   26  27 1

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