KEGG   DRUG: Denileukin diftitox
Entry
D03682                      Drug                                   
Name
Denileukin diftitox (USAN/INN);
Denileukin difitox (genetical recombination) (JAN);
Ontak (TN);
Remitoro (TN)
Product
LYMPHIR (Citius Pharmaceuticals)
Formula
C2560H4036N678O799S17
Exact mass
57605.1280
Mol weight
57640.64
Remark
Therapeutic category: 4291
ATC code: L01XX29
Product: D03682<JP/US>
Efficacy
Antineoplastic, Biological response modifier
  Disease
Cutaneous T-cell lymphoma (CD25 express) [DS:H01463]
Target
IL2RA (CD25) [HSA:3559] [KO:K05068]
  Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04144  Endocytosis
hsa04630  JAK-STAT signaling pathway
hsa05200  Pathways in cancer
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L01 ANTINEOPLASTIC AGENTS
   L01X OTHER ANTINEOPLASTIC AGENTS
    L01XX Other antineoplastic agents
     L01XX29 Denileukin diftitox
      D03682  Denileukin diftitox (USAN/INN) <JP/US>
Therapeutic category of drugs in Japan [BR:br08301]
 4  Agents affecting cellular function
  42  Antineoplastics
   429  Miscellaneous
    4291  Other Antitumors
     D03682  Denileukin diftitox (USAN/INN); Denileukin difitox (genetical recombination) (JAN)
Target-based classification of drugs [BR:br08310]
 Cytokines and receptors
  Cytokine receptors
   Interleukin receptors
    IL2RA (CD25)
     D03682  Denileukin diftitox (USAN/INN) <JP/US>
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D03682
Other DBs
CAS: 173146-27-5
PubChem: 17397778
LinkDB

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