KEGG   DRUG: Denileukin diftitoxHelp
Entry
D03682                      Drug                                   

Name
Denileukin diftitox (USAN/INN);
Denileukin difitox (genetical recombination) (JAN);
Ontak (TN)
Formula
C2560H4036N678O799S17
Exact mass
57605.128
Mol weight
57640.606
Remark
ATC code: L01XX29
Efficacy
Antineoplastic, Biological response modifier
  Disease
Cutaneous T-cell lymphoma (CD25 express) [DS:H01463]
Target
IL2RA (CD25) [HSA:3559] [KO:K05068]
  Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04144  Endocytosis
hsa04630  JAK-STAT signaling pathway
hsa05200  Pathways in cancer
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L01 ANTINEOPLASTIC AGENTS
   L01X OTHER ANTINEOPLASTIC AGENTS
    L01XX Other antineoplastic agents
     L01XX29 Denileukin diftitox
      D03682  Denileukin diftitox (USAN/INN)
USP drug classification [BR:br08302]
 Antineoplastics
  Antineoplastics, Other
   Denileukin Diftitox
    D03682  Denileukin diftitox (USAN/INN)
Target-based classification of drugs [BR:br08310]
 Cytokines and receptors
  Cytokine receptors
   Interleukin receptors
    IL2RA (CD25)
     D03682  Denileukin diftitox (USAN/INN)
Antineoplastics [br08340.html]
 D03682
BRITE hierarchy
Other DBs
CAS: 173146-27-5
PubChem: 17397778
DrugBank: DB00004
LinkDB All DBs

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