KEGG   DRUG: DexrazoxaneHelp
Entry
D03730                      Drug                                   

Name
Dexrazoxane (JAN/USAN/INN)
Formula
C11H16N4O4
Exact mass
268.1172
Mol weight
268.2691
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Remark
Therapeutic category: 3929
ATC code: V03AF02
Chemical structure group: DG01162
Product (DG01162): D03730<JP> D07807<US>
Efficacy
Antidote
Comment
Detoxifying agent for antineoplastic treatment
Target
TOP2 [HSA:7153 7155] [KO:K03164]
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 V VARIOUS
  V03 ALL OTHER THERAPEUTIC PRODUCTS
   V03A ALL OTHER THERAPEUTIC PRODUCTS
    V03AF Detoxifying agents for antineoplastic treatment
     V03AF02 Dexrazoxane
      D03730  Dexrazoxane (JAN/USAN/INN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
 3  Agents affecting metabolism
  39  Other agents affecting metabolism
   392  Antidotes
    3929  Others
     D03730  Dexrazoxane (JAN/USAN/INN)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Isomerases (EC5)
   DNA topoisomerase
    TOP2
     D03730  Dexrazoxane (JAN/USAN/INN) <JP>
Antineoplastics [br08340.html]
 D03730
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D03730
BRITE hierarchy
Other DBs
CAS: 24584-09-6
PubChem: 17397819
ChEBI: 50223
ChEMBL: CHEMBL1738
DrugBank: DB00380
LigandBox: D03730
NIKKAJI: J22.227E
LinkDB All DBs
KCF data Show

ATOM        19
            1   N1x N    11.0600  -20.0200
            2   C5x C    11.0600  -18.6200
            3   C1x C    12.2500  -17.9200
            4   N1y N    13.5100  -18.6200
            5   C1x C    13.5100  -20.0200
            6   C5x C    12.2500  -20.7200
            7   O5x O    12.2500  -22.1200
            8   O5x O     9.8700  -17.9200
            9   C1b C    14.7000  -17.9200
            10  C1c C    15.8900  -18.6200
            11  N1y N    17.0800  -17.9200
            12  C1x C    17.0800  -16.5200
            13  C5x C    18.3400  -15.8200
            14  N1x N    19.5300  -16.5200
            15  C5x C    19.5300  -17.9200
            16  C1x C    18.3400  -18.6200
            17  O5x O    20.7200  -18.6200
            18  O5x O    18.3400  -14.4200
            19  C1a C    15.8900  -20.0200
BOND        20
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     6   7 2
            8     2   8 2
            9     4   9 1
            10    9  10 1
            11   10  11 1
            12   11  12 1
            13   12  13 1
            14   13  14 1
            15   14  15 1
            16   15  16 1
            17   11  16 1
            18   15  17 2
            19   13  18 2
            20   10  19 1 #Up

» Japanese version   » Back

DBGET integrated database retrieval system