| Entry |
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| Name |
Dextrothyroxine sodium (USAN);
Choloxin (TN) |
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| Formula |
C15H10I4NO4. Na. xH2O
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| Structure |
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| Simcomp |
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| Remark |
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| Efficacy |
Antihyperlipidemic |
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| Comment |
Dextrothyroxine is D-type isomer of Levothyroxine [DR: D08125]
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| Target |
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04919 | Thyroid hormone signaling pathway |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C10 LIPID MODIFYING AGENTS
C10A LIPID MODIFYING AGENTS, PLAIN
C10AX Other lipid modifying agents
C10AX01 Dextrothyroxine
D03750 Dextrothyroxine sodium (USAN)
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Thyroid hormone like receptors
Thyroid hormone receptor (THR)
NR1A (THR)
D03750 Dextrothyroxine sodium (USAN)
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 26
1 C8y C 29.3441 -15.6972
2 O2a O 28.1394 -14.9955
3 C8x C 29.3558 -17.0890
4 C8x C 30.5604 -14.9721
5 C8y C 26.9465 -14.2880
6 C8y C 30.5721 -17.7673
7 C8y C 31.7767 -15.6504
8 C8y C 25.7361 -14.9897
9 C8y C 26.9465 -12.8786
10 C8y C 31.7884 -17.0539
11 X I 30.5897 -19.1591
12 X I 32.9756 -14.9312
13 C8x C 24.5315 -14.2880
14 X I 25.7478 -16.4046
15 C8x C 25.7361 -12.1711
16 X I 28.1571 -12.1652
17 O1a O 33.0107 -17.7322
18 C8y C 24.5315 -12.8786
19 C1b C 23.3328 -12.1652
20 C1c C 22.1340 -12.8669
21 C6a C 20.9352 -12.1594
22 O6a O 20.9410 -10.7501
23 O6a O 19.7305 -12.8611 #-
24 N1a N 22.1316 -14.2807
25 O0 O 21.5770 -17.9343
26 Z Na 17.4999 -12.8819 #+
BOND 25
1 1 2 1
2 1 3 2
3 1 4 1
4 2 5 1
5 3 6 1
6 4 7 2
7 5 8 1
8 5 9 2
9 6 10 2
10 6 11 1
11 7 12 1
12 8 13 2
13 8 14 1
14 9 15 1
15 9 16 1
16 10 17 1
17 13 18 1
18 18 19 1
19 19 20 1
20 20 21 1
21 21 22 2
22 21 23 1
23 7 10 1
24 15 18 2
25 20 24 1 #Up
BRACKET 1 19.6700 -19.0400 19.6700 -16.7300
1 22.1200 -16.7300 22.1200 -19.0400
1 x
ORIGINAL 1 25
REPEAT 1
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