| Entry |
|
|---|
| Name |
Vorozole (USAN/INN);
Rivizor (TN) |
|---|
| Formula |
C16H13ClN6
|
|---|
| Exact mass |
324.0890
|
|---|
| Mol weight |
324.77
|
|---|
| Structure |
|
|---|
| Class |
Antineoplastic
DG01596 Aromatase inhibitor
DG01524 Triazole antineoplastic
|
|---|
| Remark |
|
|---|
| Efficacy |
Antineoplastic, Estrogen biosynthesis inhibitor |
|---|
| Comment |
Aromatase inhibitor
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
L02 ENDOCRINE THERAPY
L02B HORMONE ANTAGONISTS AND RELATED AGENTS
L02BG Aromatase inhibitors
L02BG05 Vorozole
D03786 Vorozole (USAN/INN)
Drug groups [BR:br08330]
Antineoplastic
DG01596 Aromatase inhibitor
D03786 Vorozole
DG01524 Triazole antineoplastic
D03786 Vorozole
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
Cytochrome P450
CYP19A1 (ARO)
D03786 Vorozole (USAN/INN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 23
1 C8x C 29.8946 -19.6757
2 C8y C 29.8946 -21.0761
3 C8x C 31.1074 -21.7763
4 C8x C 32.3202 -21.0761
5 C8y C 32.3202 -19.6757
6 C8x C 31.1074 -18.9756
7 C1c C 33.5517 -18.9645
8 C8y C 34.7572 -19.6604
9 N4y N 33.5514 -17.5753
10 X Cl 28.6819 -21.7763
11 C8x C 34.7576 -21.0757
12 C8x C 35.9707 -21.7756
13 C8y C 37.1832 -21.0750
14 C8y C 37.1827 -19.6596
15 C8x C 35.9698 -18.9598
16 N5x N 38.5295 -21.5120
17 N5x N 39.3610 -20.3666
18 N4y N 38.5287 -19.2218
19 C1a C 38.9488 -17.9268
20 N5x N 34.6739 -16.7593
21 C8x C 34.2447 -15.4397
22 N5x N 32.8570 -15.4400
23 C8x C 32.4285 -16.7598
BOND 26
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 5 7 1
8 7 8 1
9 7 9 1 #Down
10 2 10 1
11 8 11 2
12 11 12 1
13 12 13 2
14 13 14 1
15 14 15 2
16 8 15 1
17 13 16 1
18 16 17 2
19 17 18 1
20 14 18 1
21 18 19 1
22 9 20 1
23 20 21 2
24 21 22 1
25 22 23 2
26 9 23 1
|
|---|
