KEGG   DRUG: DirithromycinHelp
Entry
D03865                      Drug                                   

Name
Dirithromycin (USP/INN);
Dynabac (TN)
Formula
C42H78N2O14
Exact mass
834.5453
Mol weight
835.0737
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Antibacterial
 DG01551  Macrolide antibiotic
  DG01874  14-membered ring macrolide antibiotic
Remark
ATC code: J01FA13
Efficacy
Antibacterial, Protein biosynthesis inhibitor
Target
50S ribosomal subunit
  Pathway
ko03010  Ribosome
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01F MACROLIDES, LINCOSAMIDES AND STREPTOGRAMINS
    J01FA Macrolides
     J01FA13 Dirithromycin
      D03865  Dirithromycin (USP/INN)
BRITE hierarchy
Other DBs
CAS: 62013-04-1
PubChem: 47205894
ChEBI: 474014
ChEMBL: CHEMBL1237072 CHEMBL3039471 CHEMBL317200
DrugBank: DB00954
LigandBox: D03865
NIKKAJI: J227.996G
LinkDB All DBs
KCF data Show

ATOM        58
            1   C1y C    29.9600  -27.4400
            2   O7x O    29.9600  -26.0400
            3   C1a C    31.1500  -25.3400
            4   C1y C    32.4100  -26.0400
            5   C1y C    32.4100  -27.4400
            6   C1z C    31.1500  -28.1400
            7   C1y C    33.6000  -25.3400
            8   N1x N    34.7200  -26.0400
            9   C1y C    34.7200  -27.4400
            10  O2x O    33.6000  -28.1400
            11  C1b C    28.7700  -28.1400
            12  C1a C    27.5800  -27.4400
            13  O6a O    27.5800  -26.0400
            14  C7x C    28.7700  -25.3400
            15  C1a C    32.1300  -29.1200
            16  O1a O    30.1700  -29.1200
            17  O2a O    37.1700  -27.4400
            18  C1b C    35.9800  -28.1400
            19  C1b C    39.5500  -27.4400
            20  C1b C    38.3600  -28.1400
            21  C1a C    41.9300  -27.4400
            22  O2a O    40.7400  -28.1400
            23  C1y C    28.7700  -24.0100
            24  C1y C    29.9600  -23.3100
            25  C1x C    32.4100  -23.3100
            26  C1y C    33.6000  -24.0100
            27  C1a C    34.7200  -23.3100
            28  C1z C    32.4100  -21.9100
            29  C1a C    33.6000  -21.2100
            30  C1y C    29.9600  -21.9100
            31  C1y C    31.1500  -21.2100
            32  C1a C    27.6500  -23.3100
            33  O2a O    27.8600  -22.1900
            34  C1y C    26.6000  -21.4900
            35  C1x C    25.4100  -22.1900
            36  C1z C    24.1500  -21.4900
            37  C1y C    24.1500  -20.0900
            38  C1y C    25.4100  -19.3900
            39  O2x O    26.6000  -20.0900
            40  C1a C    25.4100  -18.0600
            41  O2a O    22.9600  -22.1900
            42  C1a C    24.1500  -23.0300
            43  O1a O    22.9600  -19.3900
            44  C1a C    21.8400  -21.4900
            45  C1a C    28.7700  -21.2100
            46  O1a O    33.6700  -22.4000
            47  O2a O    31.1500  -19.8100
            48  C1y C    31.1500  -18.4100
            49  O2x O    32.3624  -17.7100
            50  C1y C    32.3624  -16.3100
            51  C1x C    31.1500  -15.6100
            52  C1y C    29.9376  -16.3100
            53  C1y C    29.9376  -17.7100
            54  C1a C    33.5579  -15.6196
            55  N1c N    28.7421  -15.6196
            56  O1a O    28.7421  -18.4004
            57  C1a C    27.5547  -16.3051
            58  C1a C    28.7420  -14.2103
BOND        61
            1     1   2 1
            2     4   3 1 #Up
            3     4   5 1
            4     5   6 1
            5     1   6 1
            6     4   7 1
            7     7   8 1 #Down
            8     8   9 1
            9     9  10 1
            10    5  10 1 #Up
            11    1  11 1 #Up
            12   11  12 1
            13   13  14 2
            14    2  14 1
            15    6  15 1
            16    6  16 1 #Down
            17   17  18 1
            18    9  18 1 #Up
            19   19  20 1
            20   17  20 1
            21   21  22 1
            22   19  22 1
            23   14  23 1
            24   23  24 1
            25   25  26 1
            26    7  26 1
            27   26  27 1 #Up
            28   25  28 1
            29   28  29 1 #Up
            30   24  30 1
            31   30  31 1
            32   28  31 1
            33   23  32 1 #Down
            34   24  33 1 #Down
            35   34  33 1 #Up
            36   34  35 1
            37   35  36 1
            38   36  37 1
            39   37  38 1
            40   38  39 1
            41   34  39 1
            42   38  40 1 #Down
            43   36  41 1 #Up
            44   36  42 1 #Down
            45   37  43 1 #Up
            46   41  44 1
            47   30  45 1 #Down
            48   28  46 1 #Down
            49   31  47 1 #Up
            50   48  47 1 #Up
            51   48  49 1
            52   49  50 1
            53   50  51 1
            54   51  52 1
            55   52  53 1
            56   48  53 1
            57   50  54 1 #Up
            58   52  55 1 #Up
            59   53  56 1 #Down
            60   55  57 1
            61   55  58 1

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