KEGG   DRUG: Efaproxiral sodium
Entry
D03962                      Drug                                   
Name
Efaproxiral sodium (USAN)
Formula
C20H22NO4. Na
Exact mass
363.1447
Mol weight
363.3827
Structure
Simcomp
Remark
ATC code: L01XD06
Chemical structure group: DG00709
Efficacy
Radiosensitizer
Comment
Treatment of clinical conditions characterized by tissue hypoxia including cardiovascular, surgical, and critical care conditions, Adjunctive treatment in standard radiation therapy and chemotherapy (synthetic allosteric modifier of hemoglobin)
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L01 ANTINEOPLASTIC AGENTS
   L01X OTHER ANTINEOPLASTIC AGENTS
    L01XD Sensitizers used in photodynamic/radiation therapy
     L01XD06 Efaproxiral
      D03962  Efaproxiral sodium (USAN)
Other DBs
CAS: 170787-99-2
PubChem: 47205948
LigandBox: D03962
LinkDB
KCF data

ATOM        26
            1   C8x C    15.1580  -16.9966
            2   C8y C    15.1580  -18.4016
            3   C8x C    16.3748  -19.1041
            4   C8y C    17.5916  -18.4016
            5   C8x C    17.5916  -16.9966
            6   C8y C    16.3748  -16.2940
            7   C1a C    16.3748  -14.8892
            8   C1a C    13.9413  -19.1041
            9   N1b N    18.8271  -19.1151
            10  C5a C    20.0366  -18.4169
            11  C1b C    21.2231  -19.1022
            12  O5a O    20.0370  -16.9970
            13  C8y C    22.4214  -18.4104
            14  C8x C    23.6136  -19.0988
            15  C8x C    24.8304  -18.3964
            16  C8y C    24.8305  -16.9914
            17  C8x C    23.6383  -16.3030
            18  C8x C    22.4215  -17.0054
            19  O2a O    26.0615  -16.2806
            20  C1d C    27.2730  -16.9801
            21  C6a C    28.4587  -16.2955
            22  O6a O    29.6572  -16.9876 #-
            23  O6a O    28.4587  -14.8892
            24  C1a C    26.2794  -17.9735
            25  C1a C    28.2664  -17.9735
            26  Z   Na   32.9700  -17.9200 #+
BOND        26
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     6   7 1
            8     2   8 1
            9     4   9 1
            10    9  10 1
            11   10  11 1
            12   10  12 2
            13   11  13 1
            14   13  14 2
            15   14  15 1
            16   15  16 2
            17   16  17 1
            18   17  18 2
            19   13  18 1
            20   16  19 1
            21   19  20 1
            22   20  21 1
            23   21  22 1
            24   21  23 2
            25   20  24 1
            26   20  25 1

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