| Entry |
|
|---|
| Name |
Englitazone sodium (USAN) |
|---|
| Formula |
C20H18NO3S. Na
|
|---|
| Exact mass |
375.0905
|
|---|
| Mol weight |
375.42
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
|
|---|
| Efficacy |
Antidiabetic, Peroxisome proliferator-activated receptor (PPAR) gamma agonist |
|---|
| Comment |
Thiazolidinedione derivative
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Antidiabetic agent
DG01685 Insulin sensitizer
DG01795 PPAR gamma agonist
DG01683 Thiazolidinedione
D03996 Englitazone sodium
DG02044 Hypoglycemic agent
DG01683 Thiazolidinedione
D03996 Englitazone sodium
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Thyroid hormone like receptors
Peroxisome proliferator-activated receptor (PPAR)
NR1C3 (PPARG)
D03996 Englitazone sodium (USAN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 26
1 C8x C 29.4000 -21.2800
2 C8y C 29.4000 -19.8800
3 C8x C 28.2100 -19.1800
4 C8y C 26.9500 -19.8800
5 C8y C 26.9500 -21.2800
6 C8x C 28.2100 -21.9800
7 C1x C 25.7600 -19.1800
8 C1x C 24.5700 -19.8800
9 C1y C 24.5700 -21.2800
10 O2x O 25.7600 -21.9800
11 C1b C 30.5900 -19.1800
12 C1y C 31.7800 -19.8800
13 C1b C 23.3100 -21.9800
14 C8y C 22.1200 -21.2800
15 C8x C 20.9300 -21.9800
16 C8x C 19.7400 -21.2800
17 C8x C 19.7400 -19.8800
18 C8x C 20.9300 -19.1800
19 C8x C 22.1200 -19.8800
20 S2x S 33.1100 -19.3900
21 C5x C 33.9500 -20.5100
22 N1x N 33.1800 -21.7000 #-
23 C5x C 31.7800 -21.2800
24 O5x O 35.4200 -20.5100
25 O5x O 30.5900 -21.9800
26 Z Na 32.9000 -23.1700 #+
BOND 28
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 5 10 1
12 2 11 1
13 11 12 1
14 9 13 1 #Up
15 13 14 1
16 14 15 2
17 15 16 1
18 16 17 2
19 17 18 1
20 18 19 2
21 14 19 1
22 12 20 1
23 20 21 1
24 21 22 1
25 22 23 1
26 12 23 1
27 21 24 2
28 23 25 2
|
|---|
