| Entry |
|
|---|
| Name |
Farglitazar (USAN/INN) |
|---|
| Formula |
C34H30N2O5
|
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| Exact mass |
546.2155
|
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| Mol weight |
546.61
|
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| Structure |
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| Simcomp |
|
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| Class |
Antidiabetic agent
DG01685 Insulin sensitizer
DG01795 PPAR gamma agonist
DG01732 Non-thiazolidinedione type PPAR agonist
|
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| Efficacy |
Antidiabetic, Peroxisome proliferator-activated receptor (PPAR) gamma agonist |
|---|
| Comment |
Treatment of type II diabetes (insulin action enhancer)
|
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| Target |
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| Pathway |
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| Interaction |
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| Brite |
Drug groups [BR:br08330]
Antidiabetic agent
DG01685 Insulin sensitizer
DG01795 PPAR gamma agonist
DG01732 Non-thiazolidinedione type PPAR agonist
D04132 Farglitazar
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Thyroid hormone like receptors
Peroxisome proliferator-activated receptor (PPAR)
NR1C3 (PPARG)
D04132 Farglitazar (USAN/INN)
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 41
1 C8x C 17.2200 -20.8600
2 C8y C 17.2200 -22.2600
3 C8x C 18.4324 -22.9600
4 C8x C 19.6449 -22.2600
5 C8y C 19.6449 -20.8600
6 C8x C 18.4324 -20.1600
7 O2a O 16.0076 -22.9600
8 C1b C 20.8760 -20.1490
9 C1b C 14.8121 -22.2696
10 C1b C 13.6247 -22.9551
11 C8y C 12.4335 -22.2671
12 C8y C 12.4807 -20.8602
13 O2x O 11.1610 -20.3809
14 C8y C 10.2974 -21.4880
15 N5x N 11.0834 -22.6514
16 C1a C 13.6263 -20.0855
17 C8y C 8.8909 -21.5099
18 C8x C 8.1630 -20.2936
19 C8x C 6.7631 -20.3155
20 C8x C 6.0822 -21.5388
21 C8x C 6.8102 -22.7552
22 C8x C 8.2100 -22.7332
23 C1c C 22.0812 -20.8447
24 C6a C 23.2635 -20.1619
25 N1b N 22.0816 -22.2596
26 O6a O 24.4575 -20.8512
27 O6a O 23.2635 -18.7602
28 C8y C 23.2705 -22.9459
29 C8y C 23.2709 -24.3597
30 C8x C 24.4836 -25.0593
31 C8x C 25.6958 -24.3589
32 C8x C 25.6953 -22.9451
33 C8x C 24.4827 -22.2455
34 C5a C 22.0356 -25.0737
35 O5a O 20.8278 -24.3772
36 C8y C 22.0364 -26.4599
37 C8x C 20.8346 -27.1548
38 C8x C 20.8355 -28.5548
39 C8x C 22.0484 -29.2541
40 C8x C 23.2502 -28.5592
41 C8x C 23.2493 -27.1592
BOND 45
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 2 7 1
8 5 8 1
9 7 9 1
10 9 10 1
11 10 11 1
12 11 12 2
13 12 13 1
14 13 14 1
15 14 15 2
16 11 15 1
17 12 16 1
18 14 17 1
19 17 18 2
20 18 19 1
21 19 20 2
22 20 21 1
23 21 22 2
24 17 22 1
25 8 23 1
26 23 24 1 #Up
27 23 25 1
28 24 26 1
29 24 27 2
30 25 28 1
31 28 29 2
32 29 30 1
33 30 31 2
34 31 32 1
35 32 33 2
36 28 33 1
37 29 34 1
38 34 35 2
39 34 36 1
40 36 37 2
41 37 38 1
42 38 39 2
43 39 40 1
44 40 41 2
45 36 41 1
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