KEGG   DRUG: Forasartan
Entry
D04243                      Drug                                   
Name
Forasartan (USAN/INN)
Formula
C23H28N8
Exact mass
416.2437
Mol weight
416.52
Structure
Class
Cardiovascular agent
 DG01925  Renin-angiotensin system inhibitor
  DG01495  Angiotensin II receptor antagonist
 DG03231  Antihypertensive
  DG01495  Angiotensin II receptor antagonist
Efficacy
Antihypertensive, Angiotensin II receptor antagonist
Target
AGTR1 [HSA:185] [KO:K04166]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04270  Vascular smooth muscle contraction
hsa04614  Renin-angiotensin system
Interaction
Brite
Drug groups [BR:br08330]
 Cardiovascular agent
  DG01925  Renin-angiotensin system inhibitor
   DG01495  Angiotensin II receptor antagonist
    D04243  Forasartan
  DG03231  Antihypertensive
   DG01495  Angiotensin II receptor antagonist
    D04243  Forasartan
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Angiotensin
    AGTR1
     D04243  Forasartan (USAN/INN)
Other DBs
CAS: 145216-43-9
PubChem: 47206189
ChEBI: 141552
LigandBox: D04243
NIKKAJI: J557.449H
LinkDB
KCF data

ATOM        31
            1   C8x C    22.0500  -21.0000
            2   C8y C    23.2400  -21.7000
            3   C8x C    20.7900  -21.7000
            4   C8x C    23.2400  -23.1000
            5   C1b C    24.4300  -21.0000
            6   C8y C    20.7900  -23.1000
            7   N5x N    22.0500  -23.8000
            8   C8y C    19.6000  -23.8000
            9   C8y C    18.3400  -23.1000
            10  C8x C    17.1500  -23.8000
            11  C8x C    17.1500  -25.2000
            12  C8x C    18.4100  -25.9000
            13  C8x C    19.6000  -25.2000
            14  C8y C    18.3400  -21.7000
            15  N5x N    19.5300  -20.8600
            16  N5x N    19.0400  -19.4600
            17  N5x N    17.6400  -19.4600
            18  N4x N    17.2200  -20.8600
            19  N4y N    25.6481  -21.6901
            20  N5x N    26.0775  -23.0231
            21  C8y C    27.4839  -23.0259
            22  N5x N    27.9211  -21.6892
            23  C8y C    26.7850  -20.8604
            24  C1b C    26.7848  -19.4602
            25  C1b C    28.0161  -18.7491
            26  C1b C    28.0157  -17.3601
            27  C1a C    29.2162  -16.6666
            28  C1b C    28.3152  -24.1753
            29  C1b C    29.7500  -24.1449
            30  C1b C    30.4777  -25.3460
            31  C1a C    31.8498  -25.3169
BOND        34
            1     1   2 2
            2     1   3 1
            3     2   4 1
            4     2   5 1
            5     3   6 2
            6     4   7 2
            7     6   8 1
            8     6   7 1
            9     8   9 2
            10    9  10 1
            11   10  11 2
            12   11  12 1
            13   12  13 2
            14    8  13 1
            15    9  14 1
            16   14  15 2
            17   15  16 1
            18   16  17 2
            19   17  18 1
            20   14  18 1
            21    5  19 1
            22   19  20 1
            23   20  21 2
            24   21  22 1
            25   22  23 2
            26   19  23 1
            27   23  24 1
            28   24  25 1
            29   25  26 1
            30   26  27 1
            31   21  28 1
            32   28  29 1
            33   29  30 1
            34   30  31 1

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