KEGG   DRUG: MolgramostimHelp
Entry
D05066                      Drug                                   

Name
Molgramostim (USAN/INN)
Formula
C639H1007N171O196S8
Exact mass
14468.1853
Mol weight
14477.381
Sequence
APARSPSPST QPWEHVNAIQ EARRLLNLSR DTAAEMNETV EVISEMFDLQ EPTCLQTRLE
LYKQGLRGSL TKLKGPLTMM ASHYKQHCPP TPETSCATQI ITFESFKENL KDFLLVIPFD
CWEPVQE
  Type
Peptide
Class
Cardiovascular agent
 DG01753  Colony stimulating factor
  DG01782  Granulocyte macrophage colony-stimulating factors (GM-CSF)
Remark
ATC code: L03AA03
Efficacy
Antineutropenic, Hematopoietic stimulant, Granulocyte-macrophage colony stimulating factor (GM-CSF)
Comment
Recombinant GM-CSF [HSA:1437] [KO:K05427]
Target
CSF2RA (GMCSFR, CD116) [HSA:1438] [KO:K05066]
  Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04630  JAK-STAT signaling pathway
hsa04640  Hematopoietic cell lineage
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L03 IMMUNOSTIMULANTS
   L03A IMMUNOSTIMULANTS
    L03AA Colony stimulating factors
     L03AA03 Molgramostim
      D05066  Molgramostim (USAN/INN)
Target-based classification of drugs [BR:br08310]
 Cytokines and receptors
  Cytokine receptors
   CSF and other factor receptors
    CSF2RA (GMCSFR, CD116)
     D05066  Molgramostim (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 99283-10-0
PubChem: 47206793
LinkDB All DBs

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