| Entry |
|
|---|
| Name |
Nivazol (USAN);
Nivacortol (INN) |
|---|
| Formula |
C28H31FN2O
|
|---|
| Exact mass |
430.2420
|
|---|
| Mol weight |
430.56
|
|---|
| Structure |
|
|---|
| Efficacy |
Anti-inflammatory, Glucocorticoid receptor agonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Brite |
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
NR3C1 (GR)
D05194 Nivazol (USAN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 32
1 C1y C 24.8796 -17.5248
2 C1y C 26.0499 -18.2153
3 C1z C 23.7035 -18.1976
4 C1x C 24.8213 -16.1674
5 C1y C 27.2317 -17.5365
6 C1x C 26.0499 -19.5668
7 C2y C 23.6977 -19.5551
8 C1x C 22.5333 -17.5248
9 C1a C 23.6629 -16.8227
10 C1x C 26.0733 -15.5062
11 C1z C 27.2494 -16.1908
12 C1x C 29.6248 -17.5948
13 C1x C 24.8620 -20.2515
14 C2x C 22.5333 -20.2456
15 C8y C 21.3513 -18.1976
16 C1z C 28.4255 -15.5296
17 C1a C 27.2497 -14.9094
18 C1x C 29.5956 -16.2200
19 C8y C 21.3456 -19.5551
20 C8x C 20.0641 -17.7764
21 C3b C 29.6366 -14.6812
22 O1a O 28.4429 -14.0261
23 N4y N 20.0584 -19.9705
24 N5x N 19.2566 -18.8706
25 C3a C 30.8418 -13.8327
26 C8y C 19.6350 -21.2740
27 C8x C 18.2980 -21.5587
28 C8x C 17.8659 -22.8904
29 C8y C 18.8031 -23.9304
30 C8x C 20.1401 -23.6457
31 C8x C 20.5722 -22.3141
32 X F 18.3708 -25.2625
BOND 37
1 1 2 1
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 1
7 3 8 1
8 3 9 1 #Up
9 4 10 1
10 5 11 1
11 5 12 1
12 6 13 1
13 7 14 2
14 8 15 1
15 11 16 1
16 11 17 1 #Up
17 12 18 1
18 14 19 1
19 15 20 1
20 16 21 1 #Down
21 16 22 1
22 19 23 1
23 20 24 2
24 21 25 3
25 7 13 1
26 10 11 1
27 15 19 2
28 16 18 1
29 23 24 1
30 23 26 1
31 26 27 2
32 27 28 1
33 28 29 2
34 29 30 1
35 30 31 2
36 26 31 1
37 29 32 1
|
|---|
