| Entry |
|
|---|
| Name |
Noberastine (USAN/INN) |
|---|
| Formula |
C17H21N5O
|
|---|
| Exact mass |
311.1746
|
|---|
| Mol weight |
311.38
|
|---|
| Structure |
|
|---|
| Class |
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
|
|---|
| Efficacy |
Antihistaminic, H1 receptor antagonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04750 | Inflammatory mediator regulation of TRP channels |
|
|---|
| Interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
D05196 Noberastine
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Histamine
HRH1
D05196 Noberastine (USAN/INN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 23
1 N1x N 26.7030 -19.6775
2 C1x C 27.8981 -20.3805
3 C1x C 29.1635 -19.6775
4 C1y C 29.1635 -18.2715
5 C1x C 27.8981 -17.5686
6 C1x C 26.7030 -18.2715
7 N1b N 30.3586 -17.5686
8 C8y C 31.5536 -18.2715
9 N5x N 31.5544 -19.6672
10 C8y C 32.8952 -20.0901
11 C8y C 33.6992 -18.9432
12 N4y N 32.8803 -17.8004
13 C8x C 33.5166 -21.3917
14 C8x C 34.8961 -21.3884
15 C8x C 35.7001 -20.3115
16 N5x N 35.1246 -18.9580
17 C1b C 32.8803 -16.4004
18 C8y C 34.1164 -15.6869
19 C8x C 34.1164 -14.2869
20 O2x O 35.4479 -16.1195
21 C8y C 36.2708 -14.9869
22 C8x C 35.4479 -13.8543
23 C1a C 37.6600 -14.9869
BOND 26
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 5 6 1
6 1 6 1
7 4 7 1
8 7 8 1
9 9 10 1
10 10 11 2
11 11 12 1
12 12 8 1
13 9 8 2
14 10 13 1
15 13 14 2
16 14 15 1
17 15 16 2
18 11 16 1
19 12 17 1
20 17 18 1
21 18 19 2
22 18 20 1
23 20 21 1
24 21 22 2
25 19 22 1
26 21 23 1
|
|---|
