KEGG   DRUG: Omega-3-acid ethyl esters
Entry
D05255            Mixture   Drug                                   
Name
Omega-3-acid ethyl esters (USP);
Omacor (TN)
Product
  Generic
LOVAZA (Woodward Pharma Services LLC), OMEGA-3-ACID ETHYL ESTER (Bionpharma), OMEGA-3-ACID ETHYL ESTER (Bryant Ranch Prepack), OMEGA-3-ACID ETHYL ESTERS (A-S Medication Solutions), OMEGA-3-ACID ETHYL ESTERS (A-S Medication Solutions), OMEGA-3-ACID ETHYL ESTERS (A-S Medication Solutions), OMEGA-3-ACID ETHYL ESTERS (A-S Medication Solutions), OMEGA-3-ACID ETHYL ESTERS (American Health Packaging), OMEGA-3-ACID ETHYL ESTERS (Amneal Pharmaceuticals LLC), OMEGA-3-ACID ETHYL ESTERS (Apotex Corp.), OMEGA-3-ACID ETHYL ESTERS (AvKARE), OMEGA-3-ACID ETHYL ESTERS (AvPAK), OMEGA-3-ACID ETHYL ESTERS (Bryant Ranch Prepack), OMEGA-3-ACID ETHYL ESTERS (Bryant Ranch Prepack), OMEGA-3-ACID ETHYL ESTERS (Bryant Ranch Prepack), OMEGA-3-ACID ETHYL ESTERS (Bryant Ranch Prepack), OMEGA-3-ACID ETHYL ESTERS (Camber Pharmaceuticals), OMEGA-3-ACID ETHYL ESTERS (Chartwell RX), OMEGA-3-ACID ETHYL ESTERS (EPIC PHARMA), OMEGA-3-ACID ETHYL ESTERS (Golden State Medical Supply), OMEGA-3-ACID ETHYL ESTERS (KD Pharma USA), OMEGA-3-ACID ETHYL ESTERS (KD Pharma USA), OMEGA-3-ACID ETHYL ESTERS (Lifestar Pharma LLC), OMEGA-3-ACID ETHYL ESTERS (Major Pharmaceuticals), OMEGA-3-ACID ETHYL ESTERS (PURACAP LABORATORIES LLC DBA BLU PHARMACEUTICALS), OMEGA-3-ACID ETHYL ESTERS (Par Pharmaceutical), OMEGA-3-ACID ETHYL ESTERS (Procaps S A), OMEGA-3-ACID ETHYL ESTERS (REMEDYREPACK), OMEGA-3-ACID ETHYL ESTERS (Strides Pharma Science Limited), OMEGA-3-ACID ETHYL ESTERS (XLCare Pharmaceuticals)
Component
Ethyl icosapentate [DR:D01892], Ethyl docosahexaenoate [CPD:C16185]
Class
Hypolipidemic agent
 DG01946  Hypolipidemic agent
Remark
Therapeutic category: 2189
ATC code: C10AX06
Product: D05255<JP/US>
Efficacy
Antihyperlipidemic, Triglyceride synthesis inhibitor, Lipoprotein lipase (LPL) activator, Cholesteryl ester transfer protein inhibitor
  Disease
Hypertriglyceridemia [DS:H01637]
Target
LPL [HSA:4023] [KO:K01059]
CETP [HSA:1071] [KO:K16835]
  Pathway
hsa00561  Glycerolipid metabolism
hsa03320  PPAR signaling pathway
hsa04979  Cholesterol metabolism
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C10 LIPID MODIFYING AGENTS
   C10A LIPID MODIFYING AGENTS, PLAIN
    C10AX Other lipid modifying agents
     C10AX06 Omega-3-triglycerides incl. other esters and acids
      D05255  Omega-3-acid ethyl esters (USP) <JP/US>
USP drug classification [BR:br08302]
 Cardiovascular Agents
  Dyslipidemics, Other
   Omega-3-acid Ethyl Esters
    D05255  Omega-3-acid ethyl esters (USP)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   218  Hyperlipidemia agents
    2189  Others
     D05255  Omega-3-acid ethyl esters (USP)
Drug groups [BR:br08330]
 Hypolipidemic agent
  DG01946  Hypolipidemic agent
   D05255  Omega-3-acid ethyl esters
Drug classes [BR:br08332]
 Cardiovascular agent
  DG01946  Hypolipidemic agent
   D05255  Omega-3-acid ethyl esters
Target-based classification of drugs [BR:br08310]
 Transporters
  Other transporters
   Channels and pores (TC:1)
    CETP
     D05255  Omega-3-acid ethyl esters (USP) <JP/US>
 Enzymes
  Hydrolases (EC3)
   Carboxylic-ester hydrolases
    LPL
     D05255  Omega-3-acid ethyl esters (USP) <JP/US>
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D05255
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D05255
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D05255
Other DBs
PubChem: 47206969
LinkDB

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