KEGG   DRUG: OprelvekinHelp
Entry
D05266                      Drug                                   

Name
Oprelvekin (USAN/INN);
Oprelvekin (genetical recombination) (JAN);
Neumega (TN)
Formula
C854H1411N253O235S2
Exact mass
19035.5679
Mol weight
19047.0252
Sequence
GPPPGPPRVS PDPRAELDST VLLTRSLLAD TRQLAAQLRD KFPADGDHNL DSLPTLAMSA
GALGALQLPG VLTRLRADLL SYLRHVQWLR RAGGSSLKTL EPELGTLQAR LDRLLRRLQL
LMSRLALPQP PPDPPAPPLA PPSSAWGGIR AAHAILGGLH LTLDWAVRGL LLLKTRL
  Type
Peptide
Remark
ATC code: L03AC02
Efficacy
Immunostimulant
Comment
recombinant human interleukin-11
Hematopoietic stimulant
Target
IL11RA [HSA:3590] [KO:K05056]
  Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04630  JAK-STAT signaling pathway
hsa04640  Hematopoietic cell lineage
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L03 IMMUNOSTIMULANTS
   L03A IMMUNOSTIMULANTS
    L03AC Interleukins
     L03AC02 Oprelvekin
      D05266  Oprelvekin (USAN/INN)
Target-based classification of drugs [BR:br08310]
 Cytokines and receptors
  Cytokine receptors
   Interleukin receptors
    IL11RA
     D05266  Oprelvekin (USAN/INN)
Antineoplastics [br08340.html]
 D05266
BRITE hierarchy
Other DBs
CAS: 145941-26-0
PubChem: 47206975
DrugBank: DB00038
LinkDB All DBs

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