| Entry |
|
|---|
| Name |
Parathyroid hormone (human) (USAN);
Parathyroid hormone (INN);
ALX 1-11;
Parathormone;
PTH
|
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| Product |
|
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| Formula |
C408H674N126O126S2
|
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| Exact mass |
9418.9648
|
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| Mol weight |
9424.6158
|
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| Sequence |
H-Ser Val Ser Glu Ile Gln Leu Met His Asn Leu Gly Lys His Leu Asn
Ser Met Glu Arg Val Glu Trp Leu Arg Lys Lys Leu Gln Asp Val His
Asn Phe Val Ala Leu Gly Ala Pro Leu Ala Pro Arg Asp Ala Gly Ser
Gln Arg Pro Arg Lys Lys Glu Asp Asn Val Leu Val Glu Ser His Glu
Lys Ser Leu Gly Glu Ala Asp Lys Ala Asp Val Asn Val Leu Thr Lys
Ala Lys Ser Gln-OH |
|---|
| Type |
Peptide |
|---|
| Class |
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| Remark |
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| Efficacy |
Diagnostic (pseudohypoparathyroidism, hypocalcemia), Osteoporosis agent, Parathyroid hormone receptor agonist |
|---|
| Comment |
peptide hormone
Treatment of osteoporosis, as an antiosteoporotic, in the treatment of bone and mineral disease and disorders, bone metabolism regulator, blood calcium regulator
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| Target |
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04928 | Parathyroid hormone synthesis, secretion and action |
| hsa04961 | Endocrine and other factor-regulated calcium reabsorption |
|
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| Interaction |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
H05 CALCIUM HOMEOSTASIS
H05A PARATHYROID HORMONES AND ANALOGUES
H05AA Parathyroid hormones and analogues
H05AA03 Parathyroid hormone
D05364 Parathyroid hormone (human) (USAN) <US>
USP drug classification [BR:br08302]
Metabolic Bone Disease Agents
Parathyroid Hormone
D05364 Parathyroid hormone (human) (USAN)
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Secretin receptor family
Parathyroid hormone
PTH1R
D05364 Parathyroid hormone (human) (USAN) <US>
PTH2R
D05364 Parathyroid hormone (human) (USAN) <US>
Drug classes of therapeutic agents [br08360.html]
Endocrine and hormonal agents
D05364
New drug approvals in the USA [br08319.html]
New Molecular Entity and New Therapeutic Biological Product Approvals
D05364
New drug approvals in Europe [br08329.html]
European public assessment reports (EPAR) authorised medicine
D05364
New drug approvals in the USA, Europe and Japan [br08328.html]
Approval dates by FDA, EMA and PMDA
D05364
Pharmacogenomic biomarkers [br08341.html]
Polymorphisms and germline mutations
D05364
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| Other DBs |
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| LinkDB |
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