| Entry |
|
|---|
| Name |
Piclamilast (USAN/INN) |
|---|
| Formula |
C18H18Cl2N2O3
|
|---|
| Exact mass |
380.0694
|
|---|
| Mol weight |
381.25
|
|---|
| Structure |
|
|---|
| Efficacy |
Antiasthmatic, Phosphodiesterase IV inhibitor |
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Brite |
Target-based classification of drugs [BR:br08310]
Enzymes
Hydrolases (EC3)
Phosphodiesterases
PDE4
D05474 Piclamilast (USAN/INN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 25
1 N5x N 32.8300 -8.6800
2 C8x C 32.8300 -7.2800
3 C8y C 31.5700 -6.5800
4 C8y C 30.3800 -7.2800
5 C8y C 30.3800 -8.6800
6 C8x C 31.5700 -9.4500
7 N1b N 29.1200 -6.5800
8 C5a C 27.9300 -7.2800
9 X Cl 31.5700 -5.1800
10 X Cl 29.1200 -9.4500
11 C8y C 26.7400 -6.5800
12 O5a O 27.9300 -8.6800
13 C8x C 26.7400 -5.1800
14 C8x C 25.5500 -4.4800
15 C8y C 24.2900 -5.1800
16 C8y C 24.2900 -6.5800
17 C8x C 25.5500 -7.2800
18 O2a O 23.1000 -4.4800
19 O2a O 23.1000 -7.2800
20 C1y C 23.1000 -8.6800
21 C1a C 21.9100 -5.1800
22 C1x C 21.9800 -9.5200
23 C1x C 22.4000 -10.8500
24 C1x C 23.8000 -10.8500
25 C1x C 24.2200 -9.5200
BOND 27
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 7 8 1
9 3 9 1
10 5 10 1
11 8 11 1
12 8 12 2
13 11 13 2
14 13 14 1
15 14 15 2
16 15 16 1
17 16 17 2
18 11 17 1
19 15 18 1
20 16 19 1
21 19 20 1
22 18 21 1
23 20 22 1
24 22 23 1
25 23 24 1
26 24 25 1
27 20 25 1
|
|---|
