| Entry |
|
|---|
| Name |
Progabide (USAN/INN);
Gabren (TN) |
|---|
| Formula |
C17H16ClFN2O2
|
|---|
| Exact mass |
334.0884
|
|---|
| Mol weight |
334.77
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG03199 Antiepileptic agent
DG02037 GABA mimetic antiepileptic
|
|---|
| Remark |
|
|---|
| Efficacy |
Anticonvulsant, Muscle relaxant |
|---|
| Comment |
Fatty acid derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N03 ANTIEPILEPTICS
N03A ANTIEPILEPTICS
N03AG Fatty acid derivatives
N03AG05 Progabide
D05621 Progabide (USAN/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG03199 Antiepileptic agent
DG02037 GABA mimetic antiepileptic
D05621 Progabide
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Metabotropic glutamate receptor family
GABA (metabotropic)
GABBR
D05621 Progabide (USAN/INN)
Ion channels
Ligand-gated ion channels
GABA (ionotropic)
GABRA1
D05621 Progabide (USAN/INN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 23
1 C8y C 18.6900 -15.8900
2 C8x C 18.6900 -17.2900
3 C8x C 16.2400 -17.2900
4 C8y C 16.2400 -15.8900
5 C2c C 17.4300 -15.1900
6 C8x C 19.8800 -15.1900
7 C8x C 21.0700 -15.8900
8 C8y C 21.0700 -17.2900
9 C8x C 19.8800 -17.9900
10 C8y C 14.9800 -17.9900
11 C8x C 13.7900 -17.2900
12 C8x C 13.7900 -15.8900
13 C8y C 14.9800 -15.1900
14 O1a O 14.9800 -13.7900
15 X F 14.9800 -19.3900
16 N2b N 17.4300 -13.7900
17 C1b C 18.6900 -13.0200
18 C1b C 19.8800 -13.7200
19 C1b C 21.0700 -13.0900
20 C5a C 22.2600 -13.7200
21 N1a N 23.4500 -13.0900
22 O5a O 22.2600 -15.1900
23 X Cl 22.2600 -17.9900
BOND 24
1 1 2 1
2 3 4 1
3 4 5 1
4 1 5 1
5 1 6 2
6 6 7 1
7 7 8 2
8 8 9 1
9 2 9 2
10 3 10 2
11 10 11 1
12 11 12 2
13 12 13 1
14 4 13 2
15 13 14 1
16 10 15 1
17 5 16 2
18 16 17 1
19 17 18 1
20 18 19 1
21 19 20 1
22 20 21 1
23 20 22 2
24 8 23 1
|
|---|
