| Entry |
|
|---|
| Name |
Propoxyphene napsylate (USAN);
Darvon-N (TN) |
|---|
| Formula |
C22H29NO2. C10H8O3S. H2O
|
|---|
| Exact mass |
565.2498
|
|---|
| Mol weight |
565.72
|
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| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01564 Opioid receptor agonist
DG01563 mu-Opioid receptor agonist
Analgesic
DG01984 Opioid analgesics
|
|---|
| Remark |
| Product (DG00818): | D00482<US> |
|
|---|
| Efficacy |
Analgesic |
|---|
| Comment |
Component of Darvocet (TN)
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07224 | Opioid receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N02 ANALGESICS
N02A OPIOIDS
N02AC Diphenylpropylamine derivatives
N02AC04 Dextropropoxyphene
D05632 Propoxyphene napsylate (USAN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01564 Opioid receptor agonist
DG01563 mu-Opioid receptor agonist
DG00818 Dextropropoxyphene
D05632 Propoxyphene napsylate
Analgesic
DG01984 Opioid analgesics
DG00818 Dextropropoxyphene
D05632 Propoxyphene napsylate
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Opioid
OPRM1
D05632 Propoxyphene napsylate (USAN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01564 Opioid receptor agonist
DG01563 mu-Opioid receptor agonist
DG00818 Dextropropoxyphene
Analgesic
DG01984 Opioid analgesics
DG00818 Dextropropoxyphene
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 40
1 C8x C 19.7971 -15.6634
2 C8x C 19.7971 -17.0592
3 C8x C 21.0059 -17.7571
4 C8y C 22.2146 -17.0592
5 C8y C 22.2146 -15.6634
6 C8x C 21.0059 -14.9655
7 C8x C 23.4234 -17.7571
8 C8x C 24.6322 -17.0592
9 C8y C 24.6322 -15.6634
10 C8x C 23.4234 -14.9655
11 S4a S 25.8261 -14.9739
12 O1d O 27.0349 -14.2761
13 O1d O 25.1181 -13.7471
14 O1d O 26.5133 -16.1646
15 O0 O 22.8678 -19.6414
16 C8x C 11.5597 -19.2887
17 C8x C 12.2574 -20.4748
18 C8x C 13.6528 -20.4748
19 C8x C 14.3505 -19.2887
20 C8y C 13.6528 -18.0329
21 C8x C 12.2574 -18.0329
22 C8x C 15.7458 -19.2887
23 C8y C 16.4435 -18.0329
24 C1b C 15.7458 -16.8468
25 C1d C 14.3505 -16.8468
26 C8x C 16.4435 -20.4748
27 C8x C 17.8389 -20.4748
28 C8x C 18.5366 -19.2887
29 C8x C 17.8389 -18.0329
30 O7a O 13.7226 -15.6608
31 C7a C 12.3272 -15.6608
32 O6a O 11.6295 -16.9166
33 C1b C 11.6295 -14.4747
34 C1a C 10.2341 -14.4747
35 C1c C 15.0482 -15.6608
36 C1a C 16.5133 -15.6608
37 C1b C 14.3505 -14.4049
38 N1c N 15.0482 -13.2189
39 C1a C 16.5133 -13.2189
40 C1a C 14.3505 -11.9631
BOND 41
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 7 8 2
9 8 9 1
10 9 10 2
11 5 10 1
12 9 11 1
13 11 12 1
14 11 13 2
15 11 14 2
16 16 17 2
17 17 18 1
18 18 19 2
19 19 20 1
20 20 21 2
21 16 21 1
22 22 23 1
23 23 24 1
24 25 24 1 #Down
25 25 20 1 #Up
26 22 26 2
27 26 27 1
28 27 28 2
29 28 29 1
30 23 29 2
31 25 30 1
32 30 31 1
33 31 32 2
34 31 33 1
35 33 34 1
36 25 35 1
37 35 36 1 #Up
38 35 37 1
39 37 38 1
40 38 39 1
41 38 40 1
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