KEGG   DRUG: Sargramostim
Entry
D05803                      Drug                                   

Name
Sargramostim (USP/INN);
1438 (genetical recombination) (JAN);
Leukine (TN)
Product
Class
Cardiovascular agent
 DG01753  Colony stimulating factor
  DG01782  Granulocyte macrophage colony-stimulating factors (GM-CSF)
Remark
ATC code: L03AA09
Product: D05803<US>
Efficacy
Antineutropenic, Hematopoietic stimulant, Granulocyte-macrophage colony stimulating factor (GM-CSF)
  Disease
Acute myelogenous leukemia [DS:H00003]
Comment
Recombinant GM-CSF [HSA:1437] [KO:K05427]
Target
CSF2RA (GMCSFR, CD116) [HSA:1438] [KO:K05066]
  Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04630  JAK-STAT signaling pathway
hsa04640  Hematopoietic cell lineage
hsa05200  Pathways in cancer
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L03 IMMUNOSTIMULANTS
   L03A IMMUNOSTIMULANTS
    L03AA Colony stimulating factors
     L03AA09 Sargramostim
      D05803  Sargramostim (USP/INN) <US>
USP drug classification [BR:br08302]
 Immunological Agents
  Immunostimulants
   Colony-stimulating Factors
    Sargramostim
     D05803  Sargramostim (USP/INN)
Target-based classification of drugs [BR:br08310]
 Cytokines and receptors
  Cytokine receptors
   CSF and other factor receptors
    CSF2RA (GMCSFR, CD116)
     D05803  Sargramostim (USP/INN) <US>
Other DBs
CAS: 123774-72-1
PubChem: 47207464
DrugBank: DB00020
LinkDB

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