Entry
Name
Sugammadex sodium (JAN/USAN); Bridion (TN)
Product
Formula
C72H104O48S8. 8Na
Exact mass
2176.2644
Mol weight
2178.02
Structure
Mol file KCF file DB search
Remark
Therapeutic category: 3929
Efficacy
Antidote (muscle relaxants)
Comment
Reversal agent for neuromuscular blocking agents
Interaction
DDI search
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303 ]
V VARIOUS
V03 ALL OTHER THERAPEUTIC PRODUCTS
V03A ALL OTHER THERAPEUTIC PRODUCTS
V03AB Antidotes
V03AB35 Sugammadex
D05940 Sugammadex sodium (JAN/USAN) <JP/US>
Therapeutic category of drugs in Japan [BR:br08301 ]
3 Agents affecting metabolism
39 Other agents affecting metabolism
392 Antidotes
3929 Others
D05940 Sugammadex sodium (JAN/USAN)
New drug approvals in the USA [br08319.html ]
New molecular entities and new therapeutic biological products
D05940
New drug approvals in Europe [br08329.html ]
European public assessment reports (EPAR) authorised medicine
D05940
New drug approvals in Japan [br08318.html ]
Drugs with new active ingredients
D05940
New drug approvals in the USA, Europe and Japan [br08328.html ]
Approval dates by FDA, EMA and PMDA
D05940
BRITE hierarchy
Other DBs
LinkDB
All DBs
KCF data
Show ATOM 136
1 Z Na 5.1800 -17.9200 #+
2 Z Na 7.4200 -13.7200 #+
3 Z Na 7.9100 -27.0200 #+
4 C1y C 26.8349 -13.2256
5 C1y C 27.5304 -14.4305
6 C1y C 28.9304 -14.4306
7 C1y C 29.6305 -13.2182
8 O2x O 28.9350 -12.0134
9 C1y C 27.5350 -12.0132
10 C1y C 26.7542 -23.0859
11 O2x O 27.4567 -24.3026
12 C1y C 28.8567 -24.3025
13 C1y C 29.5567 -23.0901
14 C1y C 28.8541 -21.8734
15 C1y C 27.4541 -21.8734
16 C1y C 20.8874 -24.2986
17 O2x O 22.0756 -24.9845
18 C1y C 23.2880 -24.2844
19 C1y C 23.2878 -22.8844
20 C1y C 22.0996 -22.1985
21 C1y C 20.8872 -22.8986
22 C1y C 20.8918 -12.4435
23 C1y C 20.8923 -13.8596
24 C1y C 22.1050 -14.5592
25 C1y C 23.3172 -13.8588
26 O2x O 23.3167 -12.4427
27 C1y C 22.1040 -11.7431
28 C1y C 14.9380 -13.8698
29 C1y C 16.1252 -14.5552
30 C1y C 17.3376 -13.8552
31 C1y C 17.3377 -12.4552
32 O2x O 16.1505 -11.7698
33 C1y C 14.9380 -12.4698
34 O1a O 18.5689 -14.5662
35 O2a O 19.0546 -11.7466
36 O1a O 16.1253 -15.9598
37 C1b C 13.7004 -11.7551
38 C1y C 14.9380 -22.8802
39 O2x O 14.9382 -24.2897
40 C1y C 16.1506 -24.9896
41 C1y C 17.3630 -24.2895
42 C1y C 17.3629 -22.8800
43 C1y C 16.1504 -22.1801
44 O2x O 12.5300 -17.7100
45 C1y C 12.5300 -19.1100
46 C1y C 13.7424 -19.8100
47 C1y C 14.9549 -19.1100
48 C1y C 14.9549 -17.7100
49 C1y C 13.7424 -17.0100
50 O1a O 16.1860 -16.9990
51 O2a O 13.7424 -22.1898
52 O1a O 16.1860 -19.8210
53 C1b C 11.3176 -19.8100
54 S2a S 10.1221 -19.1196
55 C1b C 8.9347 -19.8051
56 C1b C 7.7435 -19.1171
57 C6a C 6.5540 -19.8038
58 O6a O 5.3639 -19.1165 #-
59 O6a O 6.5538 -21.2098
60 O1a O 16.1505 -20.7901
61 O2a O 19.0634 -24.9882
62 O1a O 18.5688 -22.1837
63 C1b C 16.1508 -26.3899
64 O2a O 13.7424 -14.5602
65 S2a S 12.5006 -12.4478
66 C1b C 11.3155 -11.7635
67 C1b C 10.1230 -12.4521
68 C6a C 8.9343 -11.7657
69 O6a O 7.7437 -12.4532 #-
70 O6a O 8.9342 -10.3602
71 S2a S 14.9528 -27.0817
72 C1b C 13.7644 -26.3956
73 C1b C 12.5737 -27.0832
74 C6a C 11.3839 -26.3964
75 O6a O 10.1939 -27.0836 #-
76 O6a O 11.3837 -24.9902
77 O2a O 25.0742 -22.1759
78 O1a O 19.6506 -22.1847
79 O2a O 25.0849 -14.4156
80 O1a O 22.1054 -15.9599
81 C1b C 22.1038 -10.3601
82 O1a O 19.6560 -14.5743
83 C1b C 24.5194 -24.9953
84 O1a O 22.0993 -20.7902
85 O2a O 32.0767 -22.1801
86 C1y C 32.0805 -16.7882
87 C1y C 30.8476 -17.5001
88 C1y C 30.8476 -18.9001
89 C1y C 32.0600 -19.6001
90 O2x O 33.2929 -18.8882
91 C1y C 33.2929 -17.4882
92 O2a O 32.0805 -14.4082
93 C1b C 26.8405 -10.8105
94 O1a O 26.8298 -15.6436
95 O1a O 29.6204 -15.6264
96 C1b C 34.5202 -16.7793
97 O1a O 29.6521 -16.8096
98 O1a O 26.7360 -20.6299
99 O1a O 29.5652 -20.6425
100 C1b C 29.5471 -25.4983
101 O1a O 29.6521 -19.5905
102 S2a S 24.5194 -26.3899
103 C1b C 25.7173 -27.0815
104 S2a S 30.9399 -25.4982
105 C1b C 25.7175 -28.4897
106 C6a C 26.9093 -29.1779
107 O6a O 28.0945 -28.4936
108 O6a O 26.9096 -30.5897 #-
109 S2a S 35.7339 -17.4797
110 C1b C 36.9120 -16.7992
111 C1b C 38.1083 -17.4898
112 C1b C 31.6322 -26.6969
113 C1b C 33.0397 -26.6969
114 C6a C 33.7283 -27.8891
115 O6a O 35.1397 -27.8891 #-
116 O6a O 33.0439 -29.0747
117 C6a C 39.2950 -16.8044
118 O6a O 40.4868 -17.4924 #-
119 O6a O 39.2949 -15.4002
120 S2a S 20.9034 -9.6672
121 S2a S 27.5457 -9.5889
122 C1b C 28.9800 -9.5887
123 C1b C 29.6793 -8.3772
124 C1b C 20.9031 -8.2603
125 C1b C 19.7107 -7.5719
126 C6a C 31.0798 -8.3770
127 O6a O 31.7901 -9.6066
128 O6a O 31.7698 -7.1817 #-
129 C6a C 19.7104 -6.1603
130 O6a O 18.5200 -5.4732 #-
131 O6a O 20.9448 -5.4470
132 Z Na 24.7100 -30.4500 #+
133 Z Na 34.9300 -26.0400 #+
134 Z Na 16.1000 -5.3900 #+
135 Z Na 33.8100 -7.2100 #+
136 Z Na 39.9700 -19.1800 #+
BOND 136
1 4 5 1
2 5 6 1
3 6 7 1
4 7 8 1
5 8 9 1
6 4 9 1
7 10 11 1
8 11 12 1
9 12 13 1
10 13 14 1
11 14 15 1
12 10 15 1
13 16 17 1
14 17 18 1
15 18 19 1
16 19 20 1
17 20 21 1
18 16 21 1
19 22 23 1
20 23 24 1
21 24 25 1
22 25 26 1
23 26 27 1
24 22 27 1
25 28 29 1
26 29 30 1
27 30 31 1
28 31 32 1
29 32 33 1
30 28 33 1
31 30 34 1 #Down
32 31 35 1 #Down
33 29 36 1 #Up
34 33 37 1 #Up
35 38 39 1
36 39 40 1
37 40 41 1
38 41 42 1
39 42 43 1
40 38 43 1
41 44 45 1
42 45 46 1
43 46 47 1
44 47 48 1
45 48 49 1
46 44 49 1
47 48 50 1 #Down
48 46 51 1 #Down
49 47 52 1 #Up
50 45 53 1 #Up
51 53 54 1
52 54 55 1
53 55 56 1
54 56 57 1
55 57 58 1
56 57 59 2
57 38 51 1 #Down
58 43 60 1 #Down
59 41 61 1 #Down
60 42 62 1 #Up
61 40 63 1 #Up
62 49 64 1 #Down
63 28 64 1 #Down
64 37 65 1
65 65 66 1
66 66 67 1
67 67 68 1
68 68 69 1
69 68 70 2
70 22 35 1 #Down
71 63 71 1
72 71 72 1
73 72 73 1
74 73 74 1
75 74 75 1
76 74 76 2
77 16 61 1 #Down
78 19 77 1 #Down
79 21 78 1 #Down
80 25 79 1 #Down
81 24 80 1 #Down
82 27 81 1 #Up
83 23 82 1 #Up
84 18 83 1 #Up
85 20 84 1 #Up
86 86 87 1
87 87 88 1
88 88 89 1
89 89 90 1
90 90 91 1
91 86 91 1
92 89 85 1 #Down
93 10 77 1 #Down
94 13 85 1 #Down
95 4 79 1 #Down
96 7 92 1 #Down
97 86 92 1 #Down
98 9 93 1 #Up
99 5 94 1 #Up
100 6 95 1 #Down
101 91 96 1 #Up
102 87 97 1 #Up
103 15 98 1 #Down
104 14 99 1 #Up
105 12 100 1 #Up
106 88 101 1 #Down
107 83 102 1
108 102 103 1
109 100 104 1
110 103 105 1
111 105 106 1
112 106 107 2
113 106 108 1
114 96 109 1
115 109 110 1
116 110 111 1
117 104 112 1
118 112 113 1
119 113 114 1
120 114 115 1
121 114 116 2
122 111 117 1
123 117 118 1
124 117 119 2
125 81 120 1
126 93 121 1
127 121 122 1
128 122 123 1
129 120 124 1
130 124 125 1
131 123 126 1
132 126 127 2
133 126 128 1
134 125 129 1
135 129 130 1
136 129 131 2