| Entry |
|
|---|
| Name |
Sulotroban (USAN/INN) |
|---|
| Formula |
C16H17NO5S
|
|---|
| Exact mass |
335.0827
|
|---|
| Mol weight |
335.3749
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Anti-allergic agent
DG01517 Thromboxane A2 receptor antagonist
|
|---|
| Efficacy |
Antithrombotic, Thromboxane A2 (TXA2) receptor antagonist |
|---|
| Comment |
Glomerulonephritis treatment
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Anti-allergic agent
DG01517 Thromboxane A2 receptor antagonist
D05970 Sulotroban
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Thromboxane
TBXA2R
D05970 Sulotroban (USAN/INN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 23
1 C8y C 23.6875 -17.0781
2 S4a S 24.8776 -16.3781
3 C8x C 23.6875 -18.4782
4 C8x C 22.4275 -16.3781
5 N1b N 26.0677 -17.0781
6 O3c O 23.8975 -15.3981
7 O3c O 25.8576 -15.3981
8 C8x C 22.4275 -19.1783
9 C8x C 21.2375 -17.0781
10 C8x C 21.2375 -18.4782
11 C1b C 27.2785 -16.3918
12 C1b C 28.5200 -17.1213
13 C8y C 29.7029 -16.4508
14 C8x C 30.8923 -17.1502
15 C8x C 32.1103 -16.4599
16 C8y C 32.1215 -15.0600
17 C8x C 30.9320 -14.3605
18 C8x C 29.7141 -15.0508
19 O2a O 33.3502 -14.3636
20 C1b C 34.5286 -15.0567
21 C6a C 35.7353 -14.3727
22 O6a O 36.9573 -15.0919
23 O6a O 35.7463 -12.9502
BOND 24
1 1 2 1
2 1 3 1
3 1 4 2
4 2 5 1
5 2 6 2
6 2 7 2
7 3 8 2
8 4 9 1
9 8 10 1
10 9 10 2
11 5 11 1
12 11 12 1
13 12 13 1
14 13 14 2
15 14 15 1
16 15 16 2
17 16 17 1
18 17 18 2
19 13 18 1
20 16 19 1
21 19 20 1
22 20 21 1
23 21 22 1
24 21 23 2
|
|---|
