KEGG   DRUG: Teduglutide
Entry
D06053                      Drug                                   
Name
Teduglutide (USAN/INN);
Teduglutide (genetical recombination) (JAN);
Gattex (TN);
Revestive (TN)
Product
GATTEX (Takeda Pharmaceuticals America)
Formula
C164H252N44O55S
Exact mass
3749.7995
Mol weight
3752.0825
Sequence
His Gly Asp Gly Ser Phe Ser Asp Glu Met Asn Thr Ile Leu Asp Asn
Leu Ala Ala Arg Asp Phe Ile Asn Trp Leu Ile Gln Thr Lys Ile Thr
Asp
  Type
Peptide
Remark
Therapeutic category: 2499
ATC code: A16AX08
Product: D06053<JP/US>
Efficacy
Mucosal growth promotor, Glucagon-like peptide 2 receptor agonist
  Disease
Short bowel syndrome [DS:H01469]
Comment
GLP-2 [HSA:9340] [KO:K04582] analog
Treatment of intestinal diseases characterized by chemical or surgical damage of the intestinal epithelium such as Short Bowel Syndrome (SBS) or damage to the intestinal epithelium due to disease
Target
GLP2R [HSA:9340] [KO:K04582]
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A16 OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
   A16A OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
    A16AX Various alimentary tract and metabolism products
     A16AX08 Teduglutide
      D06053  Teduglutide (USAN/INN) <JP/US>
USP drug classification [BR:br08302]
 Gastrointestinal Agents
  Gastrointestinal Agents, Other
   Teduglutide
    D06053  Teduglutide (USAN/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  24  Hormones
   249  Miscellaneous
    2499  Others
     D06053  Teduglutide (USAN/INN); Teduglutide (genetical recombination) (JAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Secretin receptor family
   Glucagon
    GLP2R
     D06053  Teduglutide (USAN/INN) <JP/US>
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D06053
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D06053
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D06053
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D06053
Other DBs
CAS: 197922-42-2
PubChem: 47207711
ChEBI: 72305
LinkDB

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