KEGG   DRUG: TenofovirHelp
Entry
D06074                      Drug                                   

Name
Tenofovir (USAN);
Tenofovir hydrate
Formula
C9H14N5O4P. H2O
Exact mass
305.0889
Mol weight
305.2276
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Antiviral
 DG01890  Nucleoside reverse transcriptase inhibitor (NRTI)
 DG01656  HIV reverse transcriptase inhibitor
Transporter substrate
 DG01665  ABCB1(P-GP) substrate
 DG01913  ABCG2 substrate
Remark
Chemical structure group: DG01223
Product (DG01223): D01982<JP/US> D10605<JP/US>
Efficacy
Antiviral, Reverse transcriptase inhibitor
Target
RNA-directed DNA polymerase
Interaction
Drug interaction
Other map
map04976  Bile secretion
Brite
USP drug classification [BR:br08302]
 Antivirals
  Anti-hepatitis B (HBV) Agents
   Tenofovir
    D06074  Tenofovir (USAN)
  Anti-HIV Agents, Nucleoside and Nucleotide Reverse Transcriptase Inhibitors (NRTI)v
   Tenofovir
    D06074  Tenofovir (USAN)
BRITE hierarchy
Other DBs
CAS: 147127-20-6
PubChem: 47207732
ChEBI: 63625 63716
ChEMBL: CHEMBL3989702
LigandBox: D06074
NIKKAJI: J540.142I
LinkDB All DBs
KCF data Show

ATOM        20
            1   N5x N    27.4472  -16.0632
            2   C8x C    27.4472  -17.5298
            3   N5x N    26.2600  -18.2282
            4   C8y C    25.0028  -17.5298
            5   C8y C    25.0028  -16.0632
            6   C8y C    26.2600  -15.3648
            7   N4y N    23.6759  -17.9489
            8   C8x C    22.9076  -16.8314
            9   N5x N    23.6759  -15.6441
            10  N1a N    26.2600  -13.9680
            11  C1b C    23.6759  -19.3457
            12  C1c C    22.4886  -20.0441
            13  O2a O    21.2315  -19.3457
            14  C1b C    20.1141  -20.0441
            15  P1b P    18.8569  -19.3457
            16  C1a C    22.4886  -21.4409
            17  O1c O    17.6445  -18.6457
            18  O1c O    19.5569  -18.1332
            19  O1c O    18.1569  -20.5581
            20  O0  O    31.4281  -19.4155
BOND        20
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     4   7 1
            8     7   8 1
            9     8   9 2
            10    5   9 1
            11    6  10 1
            12    7  11 1
            13   11  12 1
            14   12  13 1
            15   13  14 1
            16   14  15 1
            17   12  16 1 #Up
            18   15  17 1
            19   15  18 2
            20   15  19 1

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