| Entry |
|
|---|
| Name |
Theofibrate (USAN);
Etofylline clofibrate (INN);
Duolip (TN) |
|---|
| Formula |
C19H21ClN4O5
|
|---|
| Exact mass |
420.1200
|
|---|
| Mol weight |
420.84
|
|---|
| Structure |
|
|---|
| Class |
|
|---|
| Efficacy |
Antihyperlipidemic, Triglyceride synthesis inhibitor, Peroxisome proliferator-activated receptor (PPAR) alpha agonist |
|---|
| Comment |
Clofibrate derivative
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Hypolipidemic agent
DG01946 Hypolipidemic agent
DG01733 PPAR alpha agonist
DG01547 Fibrate
D06102 Theofibrate
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Thyroid hormone like receptors
Peroxisome proliferator-activated receptor (PPAR)
NR1C1 (PPARA)
D06102 Theofibrate (USAN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 29
1 C8y C 24.5000 -18.3400
2 O2a O 25.7600 -17.6400
3 C1d C 26.9500 -18.3400
4 C7a C 28.1400 -17.6400
5 O7a O 29.4000 -18.3400
6 O6a O 28.1400 -16.2400
7 C1b C 30.5900 -17.6400
8 C1b C 31.7800 -18.3400
9 C8x C 23.3100 -17.6400
10 C8x C 22.0500 -18.3400
11 C8y C 22.0500 -19.7400
12 C8x C 23.2400 -20.4400
13 C8x C 24.5000 -19.7400
14 X Cl 20.8600 -20.3700
15 C1a C 25.9700 -19.3200
16 C1a C 27.9300 -19.3200
17 N4y N 31.7686 -19.7400
18 C8x C 30.9094 -20.8364
19 N5x N 31.6835 -21.9918
20 C8y C 33.0216 -21.6127
21 C8y C 33.0745 -20.2229
22 N4y N 34.2065 -22.3583
23 C8y C 35.4447 -21.7049
24 N4y N 35.4276 -20.3151
25 C8y C 34.3126 -19.5695
26 O5x O 34.2945 -18.2015
27 O5x O 36.6096 -22.4381
28 C1a C 36.6587 -19.6476
29 C1a C 34.2248 -23.7280
BOND 31
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 4 6 2
6 5 7 1
7 7 8 1
8 1 9 2
9 9 10 1
10 10 11 2
11 11 12 1
12 12 13 2
13 1 13 1
14 11 14 1
15 3 15 1
16 3 16 1
17 8 17 1
18 17 18 1
19 18 19 2
20 19 20 1
21 20 21 2
22 17 21 1
23 20 22 1
24 22 23 1
25 23 24 1
26 24 25 1
27 21 25 1
28 25 26 2
29 23 27 2
30 24 28 1
31 22 29 1
|
|---|
