| Entry |
|
|---|
| Name |
Thioguanine (USP);
Thioguanine hydrate;
Tabloid (TN);
Thioguanine (TN) |
|---|
| Product |
|
|---|
| Formula |
C5H5N5S. xH2O
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Antineoplastic
DG02018 Antimetabolite
DG01958 Nucleic acid derivative, antineoplastic
|
|---|
| Remark |
| Product (DG00684): | D06109<US> |
|
|---|
| Efficacy |
Antineoplastic, Antimetabolite |
|---|
| Disease |
Chronic myelogenous leukemia [DS: H00004] Acute nonlymphocytic leukemias [DS: H00003] |
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07041 | Antineoplastics - antimetabolic agents |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
L01 ANTINEOPLASTIC AGENTS
L01B ANTIMETABOLITES
L01BB Purine analogues
L01BB03 Tioguanine
D06109 Thioguanine (USP) <US>
USP drug classification [BR:br08302]
Antineoplastics
Antimetabolites
Thioguanine
D06109 Thioguanine (USP)
Drug groups [BR:br08330]
Antineoplastic
DG02018 Antimetabolite
DG01958 Nucleic acid derivative, antineoplastic
DG00684 Tioguanine
D06109 Thioguanine
Drug classes [BR:br08332]
Antineoplastic
DG02018 Antimetabolite
D06109 Thioguanine
Target-based classification of drugs [BR:br08310]
Enzymes
Transferases (EC2)
Pentosyltransferases
HPRT1
D06109 Thioguanine (USP) <US>
Pharmacogenomic biomarkers [br08341.html]
Polymorphisms and mutations affecting drug response
D06109
Drug groups [BR:br08330]
Antineoplastic
DG02018 Antimetabolite
DG01958 Nucleic acid derivative, antineoplastic
DG00684 Tioguanine
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 12
1 C8y C 10.4632 -17.7007
2 C8y C 10.3989 -16.2968
3 N5x N 11.6740 -18.3967
4 N4x N 9.1353 -18.1276
5 C8y C 11.6740 -15.6007
6 N5x N 9.1353 -15.8639
7 C8y C 12.8906 -17.7007
8 C8x C 8.3106 -16.9987
9 N5x N 12.8906 -16.2968
10 S1a S 11.6798 -14.1968
11 N1a N 14.1074 -18.3909
12 O0 O 19.1800 -17.0100
BOND 12
1 1 2 2
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 2
7 4 8 1
8 5 9 2
9 5 10 1
10 7 11 1
11 6 8 2
12 7 9 1
BRACKET 1 17.0100 -17.9200 17.0100 -16.0300
1 19.8100 -16.0300 19.8100 -17.9200
1 x
ORIGINAL 1 12
REPEAT 1
|
|---|
