| Entry |
|
|---|
| Name |
Tiplasinin (USAN) |
|---|
| Formula |
C24H16F3NO4
|
|---|
| Exact mass |
439.1031
|
|---|
| Mol weight |
439.38
|
|---|
| Structure |
|
|---|
| Efficacy |
Antiobesity, Plasminogen activator inhibitor-1 (PAI1) inhibitor |
|---|
| Comment |
Treatment of fibrinolytic impairment diseases
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Brite |
Target-based classification of drugs [BR:br08310]
Peptidases and inhibitors
Peptidase inhibitors
Serpin family
SERPINE1 (PAI1)
D06160 Tiplasinin (USAN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 32
1 C8y C 18.1345 -15.3363
2 C8x C 18.1345 -16.7368
3 C8x C 19.3473 -17.4370
4 C8y C 20.5603 -16.7368
5 C8y C 20.5603 -15.3363
6 C8x C 19.3473 -14.6360
7 N4y N 21.8923 -17.1695
8 C8x C 22.7155 -16.0365
9 C8y C 21.8923 -14.9035
10 C8y C 16.9217 -14.6360
11 C8x C 16.9217 -13.2357
12 C8x C 15.7087 -12.5354
13 C8y C 14.4959 -13.2357
14 C8x C 14.4959 -14.6360
15 C8x C 15.7087 -15.3363
16 O2a O 13.2809 -12.5342
17 C1d C 12.0841 -13.2254
18 X F 10.8712 -13.9256
19 X F 12.7955 -14.4580
20 X F 11.3956 -12.0323
21 C1b C 21.8923 -18.5695
22 C8y C 23.1093 -19.2723
23 C8x C 23.1089 -20.6500
24 C8x C 24.3212 -21.3502
25 C8x C 25.5338 -20.6505
26 C8x C 25.5341 -19.2729
27 C8x C 24.3219 -18.5726
28 C5a C 21.8923 -13.5035
29 C6a C 23.1151 -12.7974
30 O5a O 20.6959 -12.8128
31 O6a O 24.3216 -13.4939
32 O6a O 23.1148 -11.4101
BOND 35
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 7 8 1
9 8 9 2
10 5 9 1
11 1 10 1
12 10 11 2
13 11 12 1
14 12 13 2
15 13 14 1
16 14 15 2
17 10 15 1
18 13 16 1
19 16 17 1
20 17 18 1
21 17 19 1
22 17 20 1
23 7 21 1
24 21 22 1
25 22 23 2
26 23 24 1
27 24 25 2
28 25 26 1
29 26 27 2
30 22 27 1
31 9 28 1
32 28 29 1
33 28 30 2
34 29 31 1
35 29 32 2
|
|---|
