KEGG   DRUG: Vidarabine
Entry
D06298                      Drug                                   
Name
Vidarabine (JAN);
Vidarabine anhydrous;
ARA-A;
Armes (TN)
Formula
C10H13N5O4
Exact mass
267.0968
Mol weight
267.24
Structure
Simcomp
Class
Antiviral
 DG01440  Arabinofuranosyl type antiviral
 DG02840  Anti-herpesvirus agent
Remark
Therapeutic category: 6250
ATC code: J05AB03 S01AD06
Chemical structure group: DG00645
Product (DG00645): D06298<JP>
Efficacy
Antiviral, DNA polymerase inhibitor
Comment
Arabinofuranosyl derivative
Target
Herpesvirus DNA polymerase [KO:K18964]
  Pathway
ko03240  Viral replication
Interaction
Structure map
map07041  Antineoplastics - antimetabolic agents
map07044  Antiviral agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J05 ANTIVIRALS FOR SYSTEMIC USE
   J05A DIRECT ACTING ANTIVIRALS
    J05AB Nucleosides and nucleotides excl. reverse transcriptase inhibitors
     J05AB03 Vidarabine
      D06298  Vidarabine (JAN) <JP>
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AD Antivirals
     S01AD06 Vidarabine
      D06298  Vidarabine (JAN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  62  Chemotherapeutics
   625  Antivirals
    6250  Antivirals
     D06298  Vidarabine (JAN)
Classification of Japanese OTC drugs [BR:br08313]
 Agents for integumentary system
  91 Antivirals
   D06298  Vidarabine (JAN)
Risk category of Japanese OTC drugs [BR:br08312]
 First-class OTC drugs
  Inorganic and organic chemicals
   Vidarabine
    D06298  Vidarabine (JAN)
Drug groups [BR:br08330]
 Antiviral
  DG01440  Arabinofuranosyl type antiviral
   DG00645  Vidarabine
    D06298  Vidarabine
  DG02840  Anti-herpesvirus agent
   DG00645  Vidarabine
    D06298  Vidarabine
Drug classes [BR:br08332]
 Antiviral
  DG02840  Anti-herpesvirus agent
   D06298  Vidarabine
Antimicrobials [BR:br08307]
 Antivirals
  Genome replication inhibitor
   Herpesvirus DNA polymerase inhibitor
    D06298  Vidarabine (JAN) <JP>
Rx-to-OTC switch list in Japan [br08314.html]
 D06298
Drug groups [BR:br08330]
 Antiviral
  DG01440  Arabinofuranosyl type antiviral
   DG00645  Vidarabine
  DG02840  Anti-herpesvirus agent
   DG00645  Vidarabine
Antimicrobials abbreviations [BR:br08327]
 Antivirals
  Genome replication inhibitor
   Herpesvirus DNA polymerase inhibitor
    DG00645  Vidarabine
Other DBs
CAS: 5536-17-4
PubChem: 47207955
PDB-CCD: RAB[PDBj]
LigandBox: D06298
NIKKAJI: J3.415K
LinkDB
KCF data

ATOM        19
            1   N4y N    24.4593  -17.9096
            2   C8y C    25.5947  -18.7423
            3   C1y C    23.1374  -18.3465
            4   C8x C    24.8960  -16.5880
            5   C8y C    26.7243  -17.9213
            6   N5x N    25.7286  -20.1282
            7   O2x O    22.0020  -17.5196
            8   C1y C    22.6949  -19.6798
            9   N5x N    26.2992  -16.5880
            10  C8y C    27.9995  -18.4978
            11  C8x C    27.0039  -20.6989
            12  C1y C    20.8606  -18.3465
            13  C1y C    21.2972  -19.6798
            14  O1a O    23.5218  -20.8095
            15  N5x N    28.1393  -19.8896
            16  N1a N    29.1409  -17.6768
            17  C1b C    19.5272  -17.9096
            18  O1a O    20.4762  -20.8095
            19  O1a O    18.4907  -18.8531
BOND        21
            1     1   2 1
            2     3   1 1 #Up
            3     1   4 1
            4     2   5 2
            5     2   6 1
            6     3   7 1
            7     3   8 1
            8     4   9 2
            9     5  10 1
            10    6  11 2
            11    7  12 1
            12    8  13 1
            13    8  14 1 #Up
            14   10  15 2
            15   10  16 1
            16   12  17 1 #Up
            17   13  18 1 #Down
            18   17  19 1
            19    5   9 1
            20   11  15 1
            21   12  13 1

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