Entry |
|
Name |
Aztreonam lysine (USAN); Cayston (TN) |
Formula |
C13H17N5O8S2. C6H14N2O2
|
Exact mass |
581.1574
|
Mol weight |
581.63
|
Structure |
|
Class |
|
Remark |
Product (DG00589): | D00240<JP/US> |
|
Efficacy |
Antibacterial, Cell wall biosynthesis inhibitor |
Target |
penicillin binding protein |
Pathway |
|
Interaction |
|
Structure map |
map07012 | Cephalosporins - parenteral agents |
|
Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01D OTHER BETA-LACTAM ANTIBACTERIALS
J01DF Monobactams
J01DF01 Aztreonam
D06558 Aztreonam lysine (USAN)
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01454 Monobactam
DG00589 Aztreonam
D06558 Aztreonam lysine
DG01804 Oxyimino beta-lactam
DG00589 Aztreonam
D06558 Aztreonam lysine
Antimicrobials [BR:br08307]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
Monobactam
D06558 Aztreonam lysine (USAN)
New drug approvals in Europe [br08329.html]
European public assessment reports (EPAR) authorised medicine
D06558
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01454 Monobactam
DG00589 Aztreonam
DG01804 Oxyimino beta-lactam
DG00589 Aztreonam
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
Monobactam
DG00589 Aztreonam
|
Other DBs |
|
LinkDB |
|
KCF data |
ATOM 38
1 C1c C 23.8451 -16.5560
2 C1b C 25.0603 -15.8782
3 C6a C 22.6942 -15.8081
4 N1a N 23.8860 -17.9641
5 C1b C 26.2698 -16.5911
6 O6a O 21.4672 -16.4918
7 O6a O 22.6941 -14.4057
8 C1b C 27.4970 -15.9073
9 C1b C 28.7065 -16.6262
10 N1a N 29.9334 -15.9424
11 C2c C 11.9700 -16.5900
12 C5a C 13.1600 -17.2900
13 C8y C 10.7100 -17.2900
14 N1b N 14.3500 -16.5900
15 C1y C 15.5400 -17.2900
16 O5a O 13.1600 -18.6900
17 C8x C 9.5900 -16.5200
18 S2x S 8.4700 -17.3600
19 C8y C 8.9600 -18.6900
20 N5x N 10.3600 -18.6200
21 N1a N 8.1900 -19.8100 #+
22 N2b N 11.9700 -15.1900
23 O2a O 13.1600 -14.4900
24 C5x C 15.5400 -18.6900
25 N1y N 16.9400 -18.6900
26 C1y C 16.9400 -17.2900
27 S4a S 17.9200 -19.7400
28 O5x O 14.5600 -19.6700
29 C1a C 17.9200 -16.3100
30 O1d O 18.9700 -18.6900
31 O1d O 16.9400 -20.7200
32 O1d O 18.9700 -20.7200 #-
33 C1d C 13.1600 -13.0900
34 C1a C 13.1600 -11.6900
35 C1a C 11.7600 -13.0900
36 C6a C 14.5600 -13.0900
37 O6a O 15.2600 -14.2800
38 O6a O 15.2600 -11.9000
BOND 38
1 1 2 1
2 1 3 1
3 1 4 1 #Down
4 2 5 1
5 3 6 1
6 3 7 2
7 5 8 1
8 8 9 1
9 9 10 1
10 11 12 1
11 11 13 1
12 12 14 1
13 15 14 1 #Up
14 12 16 2
15 13 17 2
16 17 18 1
17 18 19 1
18 19 20 2
19 13 20 1
20 19 21 1
21 11 22 2
22 22 23 1
23 15 24 1
24 24 25 1
25 25 26 1
26 15 26 1
27 25 27 1
28 24 28 2
29 26 29 1 #Down
30 27 30 2
31 27 31 2
32 27 32 1
33 23 33 1
34 33 34 1
35 33 35 1
36 33 36 1
37 36 37 2
38 36 38 1
|