KEGG   DRUG: Hyaluronidase (human recombinant)
Entry
D06604                      Drug                                   
Name
Hyaluronidase (human recombinant) (USAN);
Vorhyaluronidase alfa (genetical recombination) (JAN);
Hylenex recombinant (TN)
Product
HYALURONIDASE (HF Acquisition Co LLC), HYLENEX RECOMBINANT (A-S Medication Solutions), HYLENEX RECOMBINANT (Antares Pharma)
Formula
C2327H3553N589O667S20
Exact mass
51060.6624
Mol weight
51092.9558
Sequence
LNFRAPPVIP NVPFLWAWNA PSEFCLGKFD EPLDMSLFSF IGSPRINATG QGVTIFYVDR
LGYYPYIDSI TGVTVNGGIP QKISLQDHLD KAKKDITFYM PVDNLGMAVI DWEEWRPTWA
RNWKPKDVYK NRSIELVQQQ NVQLSLTEAT EKAKQEFEKA GKDFLVETIK LGKLLRPNHL
WGYYLFPDCY NHHYKKPGYN GSCFNVEIKR NDDLSWLWNE STALYPSIYL NTQQSPVAAT
LYVRNRVREA IRVSKIPDAK SPLPVFAYTR IVFTDQVLKF LSQDELVYTF GETVALGASG
IVIWGTLSIM RSMKSCLLLD NYMETILNPY IINVTLAAKM CSQVLCQEQG VCIRKNWNSS
DYLHLNPDNF AIQLEKGGKF TVRGKPTLED LEQFSEKFYC SCYSTLSCKE KADVKDTDAV
DVCIADGVCI DAFLKPPMET EEPQIFY
(Disulfide bridge: 25-316, 189-203, 341-352, 346-400, 402-408, 423-429; Glycosylation site: 47, 131, 200, 219, 333, 358, 440)
  Type
Peptide
Remark
ATC code: B06AA03
Chemical structure group: DG00190
Product (DG00190): D04455<US> D04456<US> D06604<US>
Product (mixture): D11393<US> D11560<US> D11934<JP/US> D11967<JP/US> D12684<JP/US>
Efficacy
Adjuvant (spreading)
Comment
Hyaluronidase [KO:K01197] [EC:3.2.1.35]
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 B BLOOD AND BLOOD FORMING ORGANS
  B06 OTHER HEMATOLOGICAL AGENTS
   B06A OTHER HEMATOLOGICAL AGENTS
    B06AA Enzymes
     B06AA03 Hyaluronidase
      D06604  Hyaluronidase (human recombinant) (USAN) <US>
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D06604
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D06604
Other DBs
CAS: 757971-58-7
PubChem: 47208255
LinkDB

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