| Entry |
|
|---|
| Name |
Senicapoc (USAN) |
|---|
| Formula |
C20H15F2NO
|
|---|
| Exact mass |
323.1122
|
|---|
| Mol weight |
323.33
|
|---|
| Structure |
|
|---|
| Efficacy |
Anti-anemic (sickle cell), Potassium intermediate/small conductance calcium-activated channel antagonist |
|---|
| Comment |
Treatment of disorders mediated by a calcium activated intermediate conductance potassium ion channel antagonist
|
|---|
| Target |
|
|---|
| Brite |
Target-based classification of drugs [BR:br08310]
Ion channels
Voltage-gated ion channels
Potassium channels
KCNN4
D06640 Senicapoc (USAN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 24
1 C8x C 14.4452 -16.1718
2 C8y C 13.7470 -17.3853
3 C8x C 14.4488 -18.5967
4 C8x C 15.8488 -18.5947
5 C8y C 16.5470 -17.3812
6 C8x C 15.8452 -16.1698
7 C1d C 17.9687 -17.3790
8 C8y C 19.3493 -17.3768
9 C5a C 17.9665 -15.9806
10 C8y C 17.9709 -18.7804
11 C8x C 20.0421 -18.5726
12 C8x C 21.4421 -18.5706
13 C8y C 22.1403 -17.3572
14 C8x C 21.4476 -16.1613
15 C8x C 20.0476 -16.1634
16 C8x C 16.7618 -19.4810
17 C8x C 16.7640 -20.8810
18 C8x C 17.9775 -21.5791
19 C8x C 19.1866 -20.8785
20 C8x C 19.1845 -19.4785
21 X F 12.3470 -17.3873
22 X F 23.5515 -17.3550
23 O5a O 16.7682 -15.2909
24 N1a N 19.2108 -15.2599
BOND 26
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 5 7 1
8 7 8 1
9 7 9 1
10 7 10 1
11 8 11 2
12 11 12 1
13 12 13 2
14 13 14 1
15 14 15 2
16 8 15 1
17 10 16 2
18 16 17 1
19 17 18 2
20 18 19 1
21 19 20 2
22 10 20 1
23 2 21 1
24 13 22 1
25 9 23 2
26 9 24 1
|
|---|
