KEGG   DRUG: SodelglitazarHelp
Entry
D06647                      Drug                                   

Name
Sodelglitazar (USAN)
Formula
C23H21F4NO3S2
Exact mass
499.0899
Mol weight
499.5414
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Antidiabetic agent
 DG01685  Insulin sensitizer
  DG01795  PPAR gamma agonist
   DG01732  Non-thiazolidinedione type PPAR agonist
Other
 DG01733  PPAR agonist
  DG01732  Non-thiazolidinedione type PPAR agonist
Efficacy
Antidiabetic
Comment
Treatment of type 2 diabetes
Target
NR1C (PPAR) [HSA:5465 5467 5468] [KO:K07294 K04504 K08530]
  Pathway
hsa03320  PPAR signaling pathway
hsa04931  Insulin resistance
Interaction
Drug interaction
Brite
Target-based classification of drugs [BR:br08310]
 Nuclear receptors
  Thyroid hormone like receptors
   Peroxisome proliferator-activated receptor (PPAR)
    NR1C (PPAR)
     D06647  Sodelglitazar (USAN)
BRITE hierarchy
Other DBs
CAS: 447406-78-2
PubChem: 47208298
ChEMBL: CHEMBL2104984
LigandBox: D06647
LinkDB All DBs
KCF data Show

ATOM        33
            1   C8x C    17.0100  -21.7000
            2   C8y C    17.0100  -23.1000
            3   C8x C    18.2224  -23.8000
            4   C8x C    19.4349  -23.1000
            5   C8y C    19.4349  -21.7000
            6   C8y C    18.2224  -21.0000
            7   S2a S    15.7976  -23.8000
            8   C1b C    14.6021  -23.1096
            9   C8y C    13.4147  -23.7951
            10  C1a C    18.2224  -19.6002
            11  O2a O    20.6660  -20.9890
            12  C1d C    21.8712  -21.6847
            13  C6a C    23.0535  -21.0019
            14  O6a O    24.2475  -21.6912
            15  O6a O    23.0535  -19.6002
            16  C1a C    21.1712  -22.8971
            17  C1a C    22.5712  -22.8971
            18  S2x S    12.0926  -23.4198
            19  C8y C    11.3239  -24.5597
            20  N5x N    12.1705  -25.6431
            21  C8y C    13.4624  -25.1727
            22  C1a C    14.6198  -25.9537
            23  C8y C     9.9405  -24.5383
            24  C8y C     9.2725  -23.3394
            25  C8x C     7.8727  -23.3180
            26  C8y C     7.1543  -24.5196
            27  C8x C     7.8222  -25.7185
            28  C8x C     9.2221  -25.6699
            29  X   F     9.9952  -22.1312
            30  C1d C     5.7400  -24.4982
            31  X   F     5.7400  -23.0982
            32  X   F     4.3400  -24.4982
            33  X   F     5.7400  -25.8982
BOND        35
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     2   7 1
            8     7   8 1
            9     8   9 1
            10    6  10 1
            11    5  11 1
            12   11  12 1
            13   12  13 1
            14   13  14 1
            15   13  15 2
            16   12  16 1
            17   12  17 1
            18    9  18 1
            19   18  19 1
            20   19  20 2
            21   20  21 1
            22    9  21 2
            23   21  22 1
            24   19  23 1
            25   23  24 2
            26   24  25 1
            27   25  26 2
            28   26  27 1
            29   27  28 2
            30   23  28 1
            31   24  29 1
            32   26  30 1
            33   30  31 1
            34   30  32 1
            35   30  33 1

» Japanese version   » Back

DBGET integrated database retrieval system