| Entry |
|
|---|
| Name |
Bromopride (INN);
Movipride (TN) |
|---|
| Formula |
C14H22BrN3O2
|
|---|
| Exact mass |
343.0895
|
|---|
| Mol weight |
344.25
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
Gastrointestinal agent
DG01763 Propulsive
DG01762 Antiemetic
DG01783 Benzamide type antiemetic
|
|---|
| Remark |
|
|---|
| Efficacy |
Anti-emetic, Dopamine D2 receptor antagonist |
|---|
| Comment |
Benzamide derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A03 DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
A03F PROPULSIVES
A03FA Propulsives
A03FA04 Bromopride
D07101 Bromopride (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
D07101 Bromopride
Gastrointestinal agent
DG01763 Propulsive
D07101 Bromopride
DG01762 Antiemetic
DG01783 Benzamide type antiemetic
D07101 Bromopride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Dopamine
DRD2
D07101 Bromopride (INN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 20
1 C8y C 13.7900 -16.5200
2 C8y C 13.7900 -15.1200
3 C8x C 14.9800 -14.4200
4 C8y C 16.1700 -15.1200
5 C8y C 16.1700 -16.5200
6 C8x C 14.9800 -17.2200
7 N1a N 12.5300 -14.4200
8 X Br 12.5300 -17.2200
9 C5a C 17.4300 -17.2200
10 N1b N 18.6200 -16.5200
11 C1b C 19.8800 -17.2200
12 C1b C 21.0700 -16.5200
13 N1c N 22.2600 -17.2200
14 C1b C 23.4500 -16.5200
15 C1a C 24.7100 -17.2200
16 O2a O 17.4300 -14.4200
17 O5a O 17.4300 -18.6200
18 C1b C 22.2600 -18.6200
19 C1a C 23.5200 -19.3200
20 C1a C 17.4300 -13.0200
BOND 20
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 2 7 1
8 1 8 1
9 5 9 1
10 9 10 1
11 10 11 1
12 11 12 1
13 12 13 1
14 13 14 1
15 14 15 1
16 4 16 1
17 9 17 2
18 13 18 1
19 18 19 1
20 16 20 1
|
|---|
