KEGG   DRUG: BromoprideHelp
Entry
D07101                      Drug                                   

Name
Bromopride (INN);
Movipride (TN)
Formula
C14H22BrN3O2
Exact mass
343.0895
Mol weight
344.2474
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Neuropsychiatric agent
 DG01478  Dopamine antagonist
  DG01474  Dopamine D2-receptor antagonist
Gastrointestinal agent
 DG01763  Propulsive
 DG01762  Antiemetic
  DG01783  Benzamide type antiemetic
Remark
ATC code: A03FA04
Efficacy
Anti-emetic, Dopamine D2 receptor antagonist
Comment
Benzamide derivative
Target
DRD2 [HSA:1813] [KO:K04145]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04728  Dopaminergic synapse
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A03 DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
   A03F PROPULSIVES
    A03FA Propulsives
     A03FA04 Bromopride
      D07101  Bromopride (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Dopamine
    DRD2
     D07101  Bromopride (INN)
BRITE hierarchy
Other DBs
CAS: 4093-35-0
PubChem: 51091442
ChEMBL: CHEMBL399510
LigandBox: D07101
NIKKAJI: J8.679G
LinkDB All DBs
KCF data Show

ATOM        20
            1   C8y C    13.7900  -16.5200
            2   C8y C    13.7900  -15.1200
            3   C8x C    14.9800  -14.4200
            4   C8y C    16.1700  -15.1200
            5   C8y C    16.1700  -16.5200
            6   C8x C    14.9800  -17.2200
            7   N1a N    12.5300  -14.4200
            8   X   Br   12.5300  -17.2200
            9   C5a C    17.4300  -17.2200
            10  N1b N    18.6200  -16.5200
            11  C1b C    19.8800  -17.2200
            12  C1b C    21.0700  -16.5200
            13  N1c N    22.2600  -17.2200
            14  C1b C    23.4500  -16.5200
            15  C1a C    24.7100  -17.2200
            16  O2a O    17.4300  -14.4200
            17  O5a O    17.4300  -18.6200
            18  C1b C    22.2600  -18.6200
            19  C1a C    23.5200  -19.3200
            20  C1a C    17.4300  -13.0200
BOND        20
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     2   7 1
            8     1   8 1
            9     5   9 1
            10    9  10 1
            11   10  11 1
            12   11  12 1
            13   12  13 1
            14   13  14 1
            15   14  15 1
            16    4  16 1
            17    9  17 2
            18   13  18 1
            19   18  19 1
            20   16  20 1

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