KEGG   DRUG: MetahexamideHelp
Entry
D07117                      Drug                                   

Name
Metahexamide (INN)
Formula
C14H21N3O3S
Exact mass
311.1304
Mol weight
311.3998
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Antidiabetic agent
 DG01790  Sulfonamide hypoglycemic
  DG01734  Sulfonamide type sulfonylurea receptor agonist
 DG01508  Sulfonylurea receptor agonist
 DG02044  Hypoglycemics
  DG01790  Sulfonamide hypoglycemic
   DG01734  Sulfonamide type sulfonylurea receptor agonist
Remark
ATC code: A10BB10
Efficacy
Antidiabetic, Hypoglycemic, Sulfonylurea receptor agonist
Comment
Sulfonylurea
Target
ABCC8 (SUR1) [HSA:6833] [KO:K05032]
  Pathway
hsa02010  ABC transporters
hsa04911  Insulin secretion
hsa04930  Type II diabetes mellitus
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A10 DRUGS USED IN DIABETES
   A10B BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
    A10BB Sulfonylureas
     A10BB10 Metahexamide
      D07117  Metahexamide (INN)
Target-based classification of drugs [BR:br08310]
 Transporters
  ABC transporters
   ABCC subfamily
    ABCC8 (SUR1)
     D07117  Metahexamide (INN)
BRITE hierarchy
Other DBs
CAS: 565-33-3
PubChem: 51091456
ChEMBL: CHEMBL507419
LigandBox: D07117
NIKKAJI: J9.421H
LinkDB All DBs
KCF data Show

ATOM        21
            1   C8y C    21.7700  -11.6900
            2   C8y C    21.7700  -10.2900
            3   C8x C    23.0300   -9.5900
            4   C8y C    24.2200  -10.2900
            5   C8x C    24.2200  -11.6900
            6   C8x C    23.0300  -12.3900
            7   S4a S    25.4800   -9.5200
            8   N1b N    26.6700  -10.2200
            9   O3c O    24.5000   -8.5400
            10  O3c O    26.4600   -8.5400
            11  C5a C    27.8600   -9.5900
            12  N1b N    29.0500  -10.2200
            13  C1y C    30.2400   -9.5900
            14  O5a O    27.8600   -8.1900
            15  C1x C    30.2400   -8.1900
            16  C1x C    31.4300   -7.4200
            17  C1x C    32.6900   -8.1900
            18  C1x C    32.6900   -9.5900
            19  C1x C    31.4300  -10.2900
            20  N1a N    20.5634   -9.5800
            21  C1a C    20.5634  -12.4000
BOND        22
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     4   7 1
            8     7   8 1
            9     7   9 2
            10    7  10 2
            11    8  11 1
            12   11  12 1
            13   12  13 1
            14   11  14 2
            15   13  15 1
            16   15  16 1
            17   16  17 1
            18   17  18 1
            19   18  19 1
            20   13  19 1
            21    2  20 1
            22    1  21 1

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