| Entry |
|
|---|
| Name |
Etofibrate (INN) |
|---|
| Formula |
C18H18ClNO5
|
|---|
| Exact mass |
363.0874
|
|---|
| Mol weight |
363.7922
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
|
|---|
| Remark |
|
|---|
| Efficacy |
Antihyperlipidemic, Triglyceride synthesis inhibitor, Peroxisome proliferator-activated receptor (PPAR) alpha agonist |
|---|
| Comment |
Clofibrate derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04920 | Adipocytokine signaling pathway |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07222 | Peroxisome proliferator-activated receptor (PPAR) agonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C10 LIPID MODIFYING AGENTS
C10A LIPID MODIFYING AGENTS, PLAIN
C10AB Fibrates
C10AB09 Etofibrate
D07187 Etofibrate (INN)
Drug groups [BR:br08330]
Hypolipidemic agent
DG01946 Hypolipidemic agent
DG01733 PPAR alpha agonist
DG01547 Fibrate
D07187 Etofibrate
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Thyroid hormone like receptors
Peroxisome proliferator-activated receptor (PPAR)
NR1C1 (PPARA)
D07187 Etofibrate (INN)
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 25
1 C8x C 10.5700 -19.2500
2 C8y C 10.5700 -20.6500
3 C8x C 11.7824 -21.3500
4 C8x C 12.9949 -20.6500
5 C8y C 12.9949 -19.2500
6 C8x C 11.7824 -18.5500
7 O2a O 14.2324 -18.5500
8 C1d C 15.4449 -19.2500
9 C7a C 16.6573 -18.5500
10 O7a O 17.8697 -19.2500
11 C1b C 19.0822 -18.5500
12 C1b C 20.2946 -19.2500
13 O7a O 21.5070 -18.5500
14 C7a C 22.7195 -19.2500
15 C8y C 23.9319 -18.5500
16 C8x C 25.1504 -19.2535
17 C8x C 26.3628 -18.5535
18 C8x C 26.3629 -17.1535
19 N5x N 25.1444 -16.4500
20 C8x C 23.9319 -17.1500
21 O6a O 16.6573 -17.1500
22 O6a O 22.7195 -20.6497
23 C1a C 14.9549 -20.5324
24 C1a C 16.1449 -20.4624
25 X Cl 9.3576 -21.3500
BOND 26
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 5 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 10 11 1
12 11 12 1
13 12 13 1
14 13 14 1
15 14 15 1
16 15 16 2
17 16 17 1
18 17 18 2
19 18 19 1
20 19 20 2
21 15 20 1
22 9 21 2
23 14 22 2
24 8 23 1
25 8 24 1
26 2 25 1
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