KEGG   DRUG: ChloropyramineHelp
Entry
D07195                      Drug                                   

Name
Chloropyramine (INN)
Formula
C16H20ClN3
Exact mass
289.1346
Mol weight
289.8031
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Anti-allergic agent
 DG01557  Histamine receptor antagonist
  DG01482  Histamine receptor H1 antagonist
Remark
ATC code: D04AA09 R06AC03
Chemical structure group: DG00384
Efficacy
Antiallergic, H1 receptor antagonist
Comment
Phenbenzamine derivative
Target
HRH1 [HSA:3269] [KO:K04149]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 D DERMATOLOGICALS
  D04 ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
   D04A ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
    D04AA Antihistamines for topical use
     D04AA09 Chloropyramine
      D07195  Chloropyramine (INN)
 R RESPIRATORY SYSTEM
  R06 ANTIHISTAMINES FOR SYSTEMIC USE
   R06A ANTIHISTAMINES FOR SYSTEMIC USE
    R06AC Substituted ethylene diamines
     R06AC03 Chloropyramine
      D07195  Chloropyramine (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Histamine
    HRH1
     D07195  Chloropyramine (INN)
BRITE hierarchy
Other DBs
CAS: 59-32-5
PubChem: 51091533
ChEMBL: CHEMBL1194287
PDB-CCD: C4C[PDBj]
LigandBox: D07195
NIKKAJI: J4.599C
LinkDB All DBs
KCF data Show

ATOM        20
            1   N5x N    23.1000  -23.2400
            2   C8x C    23.1000  -24.6400
            3   C8x C    24.3124  -25.3400
            4   C8x C    25.5249  -24.6400
            5   C8x C    25.5249  -23.2400
            6   C8y C    24.3124  -22.5400
            7   N1c N    24.3124  -21.1402
            8   C1b C    23.0832  -20.4303
            9   C1b C    25.5080  -20.4498
            10  C1b C    26.6952  -21.1352
            11  N1c N    27.8866  -20.4472
            12  C1a C    29.0759  -21.1339
            13  C1a C    27.8867  -19.0403
            14  C8y C    21.8792  -21.1254
            15  C8x C    20.6963  -20.4423
            16  C8x C    19.4838  -21.1422
            17  C8y C    19.4837  -22.5422
            18  C8x C    20.6667  -23.2253
            19  C8x C    21.8791  -22.5254
            20  X   Cl   18.2545  -23.2519
BOND        21
            1     1   2 1
            2     2   3 2
            3     3   4 1
            4     4   5 2
            5     5   6 1
            6     1   6 2
            7     6   7 1
            8     7   8 1
            9     7   9 1
            10    9  10 1
            11   10  11 1
            12   11  12 1
            13   11  13 1
            14    8  14 1
            15   14  15 2
            16   15  16 1
            17   16  17 2
            18   17  18 1
            19   18  19 2
            20   14  19 1
            21   17  20 1

» Japanese version   » Back

DBGET integrated database retrieval system