| Entry |
|
|---|
| Name |
Formestane (INN);
Lentaron (TN) |
|---|
| Formula |
C19H26O3
|
|---|
| Exact mass |
302.1882
|
|---|
| Mol weight |
302.41
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Antineoplastic
DG01596 Aromatase inhibitor
|
|---|
| Remark |
|
|---|
| Efficacy |
Antineoplastic, Estrogen biosynthesis inhibitor |
|---|
| Comment |
Aromatase inhibitor
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
L02 ENDOCRINE THERAPY
L02B HORMONE ANTAGONISTS AND RELATED AGENTS
L02BG Aromatase inhibitors
L02BG02 Formestane
D07260 Formestane (INN)
Drug groups [BR:br08330]
Antineoplastic
DG01596 Aromatase inhibitor
D07260 Formestane
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
Cytochrome P450
CYP19A1 (ARO)
D07260 Formestane (INN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 22
1 C1z C 24.4300 -16.8000
2 C1y C 24.4300 -18.2000
3 C1x C 26.8549 -18.2000
4 C1x C 26.8549 -16.8000
5 C5x C 25.6424 -16.1000
6 C1x C 23.2176 -16.1000
7 C1x C 22.0051 -16.8000
8 C1y C 22.0051 -18.2000
9 C1y C 23.2176 -18.9000
10 C1z C 20.7927 -18.9000
11 C2y C 20.7927 -20.3000
12 C1x C 22.0051 -21.0000
13 C1x C 23.2176 -20.3000
14 C1x C 19.5803 -18.2000
15 C1x C 18.3678 -18.9000
16 C5x C 18.3678 -20.3000
17 C2y C 19.5803 -21.0000
18 O5x O 17.1347 -21.0122
19 O5x O 25.6424 -14.7002
20 O1a O 19.5803 -22.3999
21 C1a C 20.7927 -17.5000
22 C1a C 24.4300 -15.4000
BOND 25
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 1 5 1
6 1 6 1
7 6 7 1
8 7 8 1
9 8 9 1
10 9 2 1
11 8 10 1
12 10 11 1
13 11 12 1
14 12 13 1
15 13 9 1
16 10 14 1
17 14 15 1
18 15 16 1
19 16 17 1
20 17 11 2
21 16 18 2
22 5 19 2
23 17 20 1
24 10 21 1 #Up
25 1 22 1 #Up
|
|---|
