| Entry |
|
|---|
| Name |
Melperone (INN);
Bunil (TN) |
|---|
| Formula |
C16H22FNO
|
|---|
| Exact mass |
263.1685
|
|---|
| Mol weight |
263.3504
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG03200 Antipsychotic agent
DG01940 Butyrophenone derivative
|
|---|
| Remark |
|
|---|
| Efficacy |
Neuroleptic |
|---|
| Comment |
Butyrophenone derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N05 PSYCHOLEPTICS
N05A ANTIPSYCHOTICS
N05AD Butyrophenone derivatives
N05AD03 Melperone
D07309 Melperone (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG03200 Antipsychotic agent
DG01940 Butyrophenone derivative
DG00887 Melperone
D07309 Melperone
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Dopamine
DRD2
D07309 Melperone (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG03200 Antipsychotic agent
DG01940 Butyrophenone derivative
DG00887 Melperone
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 19
1 C8x C 15.0500 -19.6000
2 C8y C 15.0500 -21.0000
3 C8x C 16.2624 -21.7000
4 C8x C 17.4749 -21.0000
5 C8y C 17.4749 -19.6000
6 C8x C 16.2624 -18.9000
7 C5a C 18.7124 -18.9000
8 C1b C 19.9249 -19.6000
9 C1b C 21.1373 -18.9000
10 C1b C 22.3497 -19.6000
11 N1y N 23.5622 -18.9000
12 C1x C 24.7953 -19.6122
13 C1x C 26.0079 -18.9124
14 C1y C 26.0081 -17.5124
15 C1x C 24.7750 -16.8002
16 C1x C 23.5624 -17.5000
17 X F 13.8376 -21.7000
18 O5a O 18.7186 -17.5003
19 C1a C 27.2499 -16.7956
BOND 20
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 5 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 10 11 1
12 11 12 1
13 12 13 1
14 13 14 1
15 14 15 1
16 15 16 1
17 11 16 1
18 2 17 1
19 7 18 2
20 14 19 1
|
|---|
