KEGG   DRUG: OxomemazineHelp
Entry
D07401                      Drug                                   

Name
Oxomemazine (INN);
Doxergan (TN)
Formula
C18H22N2O2S
Exact mass
330.1402
Mol weight
330.4445
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Remark
ATC code: R06AD08
Efficacy
Antiallergic, H1 receptor antagonist
Comment
Phenothiazine derivative
Target
HRH1 [HSA:3269] [KO:K04149]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04750  Inflammatory mediator regulation of TRP channels
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 R RESPIRATORY SYSTEM
  R06 ANTIHISTAMINES FOR SYSTEMIC USE
   R06A ANTIHISTAMINES FOR SYSTEMIC USE
    R06AD Phenothiazine derivatives
     R06AD08 Oxomemazine
      D07401  Oxomemazine (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Histamine
    HRH1
     D07401  Oxomemazine (INN)
BRITE hierarchy
Other DBs
CAS: 3689-50-7
PubChem: 51091737
ChEMBL: CHEMBL2104734
LigandBox: D07401
NIKKAJI: J8.210D
LinkDB All DBs
KCF data Show

ATOM        23
            1   C8x C    22.6800  -20.3000
            2   C8x C    22.6800  -18.8300
            3   C8x C    23.9400  -18.1300
            4   C8y C    25.1300  -18.8300
            5   C8y C    25.1300  -20.3000
            6   C8x C    23.9400  -21.0000
            7   N4y N    26.3200  -18.1300
            8   C8y C    27.5800  -18.8300
            9   C8y C    27.5800  -20.3000
            10  S2x S    26.3200  -21.0000
            11  C8x C    28.7700  -18.1300
            12  C8x C    30.0300  -18.8300
            13  C8x C    30.0300  -20.3000
            14  C8x C    28.7700  -21.0000
            15  C1b C    26.3200  -16.7300
            16  C1c C    27.5800  -16.0300
            17  C1b C    28.7700  -16.7300
            18  N1c N    29.9600  -16.0300
            19  C1a C    27.5800  -14.6300
            20  C1a C    31.1500  -16.7300
            21  C1a C    29.9600  -14.6300
            22  O3c O    27.0200  -22.1900
            23  O3c O    25.6200  -22.1900
BOND        25
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     4   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11    5  10 1
            12    8  11 2
            13   11  12 1
            14   12  13 2
            15   13  14 1
            16    9  14 2
            17    7  15 1
            18   15  16 1
            19   16  17 1
            20   17  18 1
            21   16  19 1
            22   18  20 1
            23   18  21 1
            24   10  22 2
            25   10  23 2

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