KEGG DRUG: Antazoline

DRUG: Antazoline

Entry

D07458                      Drug

Name

Antazoline (INN)

Formula

C17H19N3

Exact mass

265.1579

Mol weight

265.35

Structure

Simcomp

Class

Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist

Remark

ATC code:

R01AC04 R06AX05

Chemical structure group:

DG01037

Efficacy

Antiallergic, H1 receptor antagonist

Target

HRH1 [HSA:3269] [KO:K04149]

Pathway

hsa04020

Calcium signaling pathway

hsa04080

Neuroactive ligand-receptor interaction

Interaction

Brite

Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
R RESPIRATORY SYSTEM
  R01 NASAL PREPARATIONS
   R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
    R01AC Antiallergic agents, excl. corticosteroids
     R01AC04 Antazoline
      D07458  Antazoline (INN)
  R06 ANTIHISTAMINES FOR SYSTEMIC USE
   R06A ANTIHISTAMINES FOR SYSTEMIC USE
    R06AX Other antihistamines for systemic use
     R06AX05 Antazoline
      D07458  Antazoline (INN)
Drug groups [BR:br08330]
Anti-allergic agent
  DG01557  Histamine receptor antagonist
   DG01482  Histamine receptor H1 antagonist
    DG01037  Antazoline
     D07458  Antazoline
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
  Rhodopsin family
   Histamine
    HRH1
     D07458  Antazoline (INN)
Drug groups [BR:br08330]
Anti-allergic agent
  DG01557  Histamine receptor antagonist
   DG01482  Histamine receptor H1 antagonist
    DG01037  Antazoline

Other DBs

CAS:

91-75-8

PubChem:

ChEBI:

LigandBox:

NIKKAJI:

LinkDB

KCF data

ATOM        20
            1   C8y C    16.4015  -14.4572
            2   C8x C    16.4015  -15.8545
            3   C8x C    17.5892  -16.5531
            4   C8y C    18.8467  -15.8545
            5   N1c N    18.8467  -14.4572
            6   C1b C    17.5892  -13.7586
            7   C8x C    20.0343  -16.5531
            8   N1x N    21.2220  -15.8545
            9   C2y C    21.2220  -14.4572
            10  C1b C    20.0343  -13.7586
            11  C8x C    15.2139  -13.7586
            12  C8x C    13.9563  -14.4572
            13  C8x C    13.9563  -15.8545
            14  C8x C    15.2139  -16.5531
            15  C8x C    17.5892  -17.9503
            16  C8x C    18.8467  -18.6489
            17  C8x C    20.0343  -17.9503
            18  C1x C    22.5494  -16.2736
            19  C1x C    23.3877  -15.1558
            20  N2x N    22.5494  -14.0380
BOND        22
            1     1   2 1
            2     3   4 1
            3     4   5 1
            4     5   6 1
            5     1   6 1
            6     4   7 2
            7     8   9 1
            8     9  10 1
            9     5  10 1
            10    1  11 2
            11   11  12 1
            12   12  13 2
            13   13  14 1
            14   14   2 2
            15    3  15 2
            16   15  16 1
            17   16  17 2
            18   17   7 1
            19    8  18 1
            20   18  19 1
            21   19  20 1
            22    9  20 2

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