| Entry |
|
|---|
| Name |
Alizapride hydrochloride;
Plitican (TN) |
|---|
| Formula |
C16H21N5O2. HCl
|
|---|
| Exact mass |
351.1462
|
|---|
| Mol weight |
351.83
|
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| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
Gastrointestinal agent
DG01763 Propulsive
DG01762 Antiemetic
DG01783 Benzamide type antiemetic
|
|---|
| Remark |
|
|---|
| Efficacy |
Anti-emetic, Dopamine D2 receptor antagonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A03 DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
A03F PROPULSIVES
A03FA Propulsives
A03FA05 Alizapride
D07563 Alizapride hydrochloride
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG00058 Alizapride
D07563 Alizapride hydrochloride
Gastrointestinal agent
DG01763 Propulsive
DG00058 Alizapride
D07563 Alizapride hydrochloride
DG01762 Antiemetic
DG01783 Benzamide type antiemetic
DG00058 Alizapride
D07563 Alizapride hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Dopamine
DRD2
D07563 Alizapride hydrochloride
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG00058 Alizapride
Gastrointestinal agent
DG01763 Propulsive
DG00058 Alizapride
DG01762 Antiemetic
DG01783 Benzamide type antiemetic
DG00058 Alizapride
|
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| Other DBs |
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|---|
| LinkDB |
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| KCF data |
ATOM 24
1 X Cl 24.2966 -14.3464
2 C8y C 15.5400 -16.1700
3 C8y C 15.5400 -17.5000
4 C8x C 14.4200 -18.2000
5 C8y C 13.2300 -17.5000
6 C8y C 13.2300 -16.1700
7 C8x C 14.4200 -15.5400
8 N4x N 11.9700 -15.4700
9 N5x N 11.9700 -18.2000
10 N5x N 10.8500 -16.8000
11 O2a O 16.7300 -15.5400
12 C5a C 16.7300 -18.2000
13 N1b N 17.8500 -17.5000
14 C1b C 19.0400 -18.2000
15 O5a O 16.7300 -19.5300
16 C1a C 16.7300 -14.1400
17 C1y C 20.2300 -17.5000
18 N1y N 21.3500 -18.2700
19 C1x C 22.4700 -17.4300
20 C1x C 21.9800 -16.1700
21 C1x C 20.6500 -16.1700
22 C1b C 21.4200 -19.6700
23 C2b C 22.6800 -20.3700
24 C2a C 23.8700 -19.6000
BOND 25
1 2 3 2
2 3 4 1
3 4 5 2
4 5 6 1
5 6 7 2
6 2 7 1
7 6 8 1
8 5 9 1
9 8 10 1
10 10 9 2
11 2 11 1
12 3 12 1
13 12 13 1
14 13 14 1
15 12 15 2
16 11 16 1
17 14 17 1
18 17 18 1
19 18 19 1
20 19 20 1
21 20 21 1
22 17 21 1
23 18 22 1
24 22 23 1
25 23 24 2
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