KEGG   DRUG: Alizapride hydrochloride
Entry
D07563                      Drug                                   
Name
Alizapride hydrochloride;
Plitican (TN)
Formula
C16H21N5O2. HCl
Exact mass
351.1462
Mol weight
351.8312
Structure
Simcomp
Class
Neuropsychiatric agent
 DG01478  Dopamine antagonist
  DG01474  Dopamine D2-receptor antagonist
Gastrointestinal agent
 DG01763  Propulsive
 DG01762  Antiemetic
  DG01783  Benzamide type antiemetic
Remark
ATC code: A03FA05
Chemical structure group: DG00058
Efficacy
Anti-emetic, Dopamine D2 receptor antagonist
Target
DRD2 [HSA:1813] [KO:K04145]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04728  Dopaminergic synapse
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A03 DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
   A03F PROPULSIVES
    A03FA Propulsives
     A03FA05 Alizapride
      D07563  Alizapride hydrochloride
Drug groups [BR:br08330]
 Neuropsychiatric agent
  DG01478  Dopamine antagonist
   DG01474  Dopamine D2-receptor antagonist
    DG00058  Alizapride
     D07563  Alizapride hydrochloride
 Gastrointestinal agent
  DG01763  Propulsive
   DG00058  Alizapride
    D07563  Alizapride hydrochloride
  DG01762  Antiemetic
   DG01783  Benzamide type antiemetic
    DG00058  Alizapride
     D07563  Alizapride hydrochloride
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Dopamine
    DRD2
     D07563  Alizapride hydrochloride
Drug groups [BR:br08330]
 Neuropsychiatric agent
  DG01478  Dopamine antagonist
   DG01474  Dopamine D2-receptor antagonist
    DG00058  Alizapride
 Gastrointestinal agent
  DG01763  Propulsive
   DG00058  Alizapride
  DG01762  Antiemetic
   DG01783  Benzamide type antiemetic
    DG00058  Alizapride
Other DBs
CAS: 59338-87-3
PubChem: 51091884
LigandBox: D07563
LinkDB
KCF data

ATOM        24
            1   X   Cl   24.2966  -14.3464
            2   C8y C    15.5400  -16.1700
            3   C8y C    15.5400  -17.5000
            4   C8x C    14.4200  -18.2000
            5   C8y C    13.2300  -17.5000
            6   C8y C    13.2300  -16.1700
            7   C8x C    14.4200  -15.5400
            8   N4x N    11.9700  -15.4700
            9   N5x N    11.9700  -18.2000
            10  N5x N    10.8500  -16.8000
            11  O2a O    16.7300  -15.5400
            12  C5a C    16.7300  -18.2000
            13  N1b N    17.8500  -17.5000
            14  C1b C    19.0400  -18.2000
            15  O5a O    16.7300  -19.5300
            16  C1a C    16.7300  -14.1400
            17  C1y C    20.2300  -17.5000
            18  N1y N    21.3500  -18.2700
            19  C1x C    22.4700  -17.4300
            20  C1x C    21.9800  -16.1700
            21  C1x C    20.6500  -16.1700
            22  C1b C    21.4200  -19.6700
            23  C2b C    22.6800  -20.3700
            24  C2a C    23.8700  -19.6000
BOND        25
            1     2   3 2
            2     3   4 1
            3     4   5 2
            4     5   6 1
            5     6   7 2
            6     2   7 1
            7     6   8 1
            8     5   9 1
            9     8  10 1
            10   10   9 2
            11    2  11 1
            12    3  12 1
            13   12  13 1
            14   13  14 1
            15   12  15 2
            16   11  16 1
            17   14  17 1
            18   17  18 1
            19   18  19 1
            20   19  20 1
            21   20  21 1
            22   17  21 1
            23   18  22 1
            24   22  23 1
            25   23  24 2

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