KEGG   DRUG: CarbimazoleHelp
Entry
D07616                      Drug                                   

Name
Carbimazole (INN);
Carbimazol henning (TN)
Formula
C7H10N2O2S
Exact mass
186.0463
Mol weight
186.2315
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Other
 DG01934  Antithyroid agent
Remark
Same as: C07615
ATC code: H03BB01
Efficacy
Antithyroid, Thyroid hormone synthesis inhibitor
Target
TPO [HSA:7173] [KO:K00431]
  Pathway
hsa04918  Thyroid hormone synthesis
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
  H03 THYROID THERAPY
   H03B ANTITHYROID PREPARATIONS
    H03BB Sulfur-containing imidazole derivatives
     H03BB01 Carbimazole
      D07616  Carbimazole (INN)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Oxidoreductases (EC1)
   Thyroid peroxidase
    TPO
     D07616  Carbimazole (INN)
BRITE hierarchy
Other DBs
CAS: 22232-54-8
PubChem: 51091925
ChEBI: 617099
ChEMBL: CHEMBL508102
DrugBank: DB00389
LigandBox: D07616
NIKKAJI: J11.419G
LinkDB All DBs
KCF data Show

ATOM        12
            1   N4y N    24.7100  -17.3600
            2   C8y C    25.9000  -18.2000
            3   C8x C    23.5900  -18.2700
            4   C7a C    24.7100  -15.9600
            5   N4y N    25.4800  -19.5300
            6   S0  S    27.2300  -17.7100
            7   C8x C    24.0800  -19.5300
            8   O7a O    23.5200  -15.3300
            9   O6a O    25.9000  -15.2600
            10  C1a C    26.3200  -20.6500
            11  C1b C    22.2600  -16.0300
            12  C1a C    21.0700  -15.3300
BOND        12
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 2
            6     3   7 2
            7     4   8 1
            8     4   9 2
            9     5  10 1
            10    8  11 1
            11   11  12 1
            12    5   7 1

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