KEGG   DRUG: CeftizoximeHelp
Entry
D07658                      Drug                                   

Name
Ceftizoxime (INN);
CZX
Formula
C13H13N5O5S2
Exact mass
383.0358
Mol weight
383.4028
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Antibacterial
 DG01710  beta-Lactam antibiotic
  DG01714  Cephalosporin skeleton group
   DG01488  Cephem
 DG01776  Third-generation cephalosporin
 DG01804  Oxyimino beta-lactam
Transporter substrate
 DG02860  SLC22A8 (OAT3) substrate
Remark
Same as: C06890
ATC code: J01DD07
Chemical structure group: DG00576
Product (DG00576): D00923<JP>
Efficacy
Antibacterial, Cell wall biosynthesis inhibitor
Target
penicillin binding protein
  Pathway
ko00550  Peptidoglycan biosynthesis
Metabolism
Transporter: SLC22A8 [HSA:9376]
Interaction
Drug interaction
Structure map
map07012  Cephalosporins - parenteral agents
map07013  Cephalosporins - oral agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01D OTHER BETA-LACTAM ANTIBACTERIALS
    J01DD Third-generation cephalosporins
     J01DD07 Ceftizoxime
      D07658  Ceftizoxime (INN)
Prodrugs [br08324.html]
 D07658
BRITE hierarchy
Other DBs
CAS: 68401-81-0
PubChem: 51091962
ChEBI: 553473
ChEMBL: CHEMBL528
DrugBank: DB01332
LigandBox: D07658
NIKKAJI: J37.178E
LinkDB All DBs
KCF data Show

ATOM        25
            1   C1y C    27.3700  -17.9200
            2   N1y N    27.3700  -19.2500
            3   C2y C    28.6300  -19.9500
            4   C2x C    29.8200  -19.2500
            5   C1x C    29.8200  -17.9200
            6   S2x S    28.6300  -17.2200
            7   C1y C    25.9700  -17.9200
            8   C5x C    25.9700  -19.2500
            9   N1b N    24.7800  -17.2200
            10  C5a C    23.5900  -17.9200
            11  O5a O    23.5900  -19.2500
            12  O5x O    24.7800  -19.9500
            13  C2c C    22.4000  -17.2200
            14  C8y C    21.1400  -17.9200
            15  C8x C    20.0200  -17.0800
            16  S2x S    18.9000  -17.9200
            17  C8y C    19.3200  -19.3200
            18  N5x N    20.7200  -19.2500
            19  N2b N    22.4000  -15.7500
            20  C6a C    28.6300  -21.4200
            21  O6a O    29.8200  -22.1200
            22  O6a O    27.3700  -22.1200
            23  N1a N    18.4800  -20.4400
            24  O2a O    23.5900  -15.1200
            25  C1a C    23.5900  -13.7200
BOND        27
            1     1   2 1
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     1   7 1
            8     7   8 1
            9     2   8 1
            10    7   9 1 #Up
            11    9  10 1
            12   10  11 2
            13    8  12 2
            14   10  13 1
            15   13  14 1
            16   14  15 2
            17   15  16 1
            18   16  17 1
            19   17  18 2
            20   14  18 1
            21   13  19 2
            22    3  20 1
            23   20  21 1
            24   20  22 2
            25   17  23 1
            26   19  24 1
            27   24  25 1

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