| Entry |
|
|---|
| Name |
Ceftizoxime (INN) |
|---|
| Formula |
C13H13N5O5S2
|
|---|
| Exact mass |
383.0358
|
|---|
| Mol weight |
383.41
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Antibacterial
DG01710 beta-Lactam antibiotic
DG01714 Cephalosporin skeleton group
DG01488 Cephem
DG01776 Third-generation cephalosporin
DG01804 Oxyimino beta-lactam
Transporter substrate
DG02860 SLC22A8 substrate
|
|---|
| Remark |
| Product (DG00576): | D00923<JP> |
|
|---|
| Efficacy |
Antibacterial, Cell wall biosynthesis inhibitor |
|---|
| Target |
penicillin binding protein |
|---|
| Pathway |
|
|---|
| Metabolism |
Transporter: SLC22A8 [HSA: 9376]
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07012 | Cephalosporins - parenteral agents |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01D OTHER BETA-LACTAM ANTIBACTERIALS
J01DD Third-generation cephalosporins
J01DD07 Ceftizoxime
D07658 Ceftizoxime (INN)
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01714 Cephalosporin skeleton group
DG01488 Cephem
DG00576 Ceftizoxime
D07658 Ceftizoxime
DG01776 Third-generation cephalosporin
DG00576 Ceftizoxime
D07658 Ceftizoxime
DG01804 Oxyimino beta-lactam
DG00576 Ceftizoxime
D07658 Ceftizoxime
Transporter substrate
DG02860 SLC22A8 substrate
D07658 Ceftizoxime
Antimicrobials [BR:br08307]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
Third-generation cephalosporin
D07658 Ceftizoxime (INN)
Drug metabolizing enzymes and transporters [br08309.html]
Drug transporters
D07658
Prodrugs [br08324.html]
D07658
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01714 Cephalosporin skeleton group
DG01488 Cephem
DG00576 Ceftizoxime
DG01776 Third-generation cephalosporin
DG00576 Ceftizoxime
DG01804 Oxyimino beta-lactam
DG00576 Ceftizoxime
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
Third-generation cephalosporin
DG00576 Ceftizoxime
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 25
1 C1y C 27.3700 -17.9200
2 N1y N 27.3700 -19.2500
3 C2y C 28.6300 -19.9500
4 C2x C 29.8200 -19.2500
5 C1x C 29.8200 -17.9200
6 S2x S 28.6300 -17.2200
7 C1y C 25.9700 -17.9200
8 C5x C 25.9700 -19.2500
9 N1b N 24.7800 -17.2200
10 C5a C 23.5900 -17.9200
11 O5a O 23.5900 -19.2500
12 O5x O 24.7800 -19.9500
13 C2c C 22.4000 -17.2200
14 C8y C 21.1400 -17.9200
15 C8x C 20.0200 -17.0800
16 S2x S 18.9000 -17.9200
17 C8y C 19.3200 -19.3200
18 N5x N 20.7200 -19.2500
19 N2b N 22.4000 -15.7500
20 C6a C 28.6300 -21.4200
21 O6a O 29.8200 -22.1200
22 O6a O 27.3700 -22.1200
23 N1a N 18.4800 -20.4400
24 O2a O 23.5900 -15.1200
25 C1a C 23.5900 -13.7200
BOND 27
1 1 2 1
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 1
6 1 6 1
7 1 7 1
8 7 8 1
9 2 8 1
10 7 9 1 #Up
11 9 10 1
12 10 11 2
13 8 12 2
14 10 13 1
15 13 14 1
16 14 15 2
17 15 16 1
18 16 17 1
19 17 18 2
20 14 18 1
21 13 19 2
22 3 20 1
23 20 21 1
24 20 22 2
25 17 23 1
26 19 24 1
27 24 25 1
|
|---|
