| Entry |
|
|---|
| Name |
Clocapramine (INN) |
|---|
| Formula |
C28H37ClN4O
|
|---|
| Exact mass |
480.2656
|
|---|
| Mol weight |
481.07
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG03200 Antipsychotic agent
DG01942 Iminobenzyl antipsychotic
|
|---|
| Remark |
| Product (DG01313): | D02371<JP> |
|
|---|
| Efficacy |
Antipsychotic, Neuroleptic, Dopamine D2 receptor antagonist |
|---|
| Comment |
Iminodibenzyl derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07213 | Dopamine receptor agonists/antagonists |
|
|---|
| Brite |
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG01313 Clocapramine
D07718 Clocapramine
DG03200 Antipsychotic agent
DG01942 Iminobenzyl antipsychotic
DG01313 Clocapramine
D07718 Clocapramine
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Dopamine
DRD2
D07718 Clocapramine (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG01313 Clocapramine
DG03200 Antipsychotic agent
DG01942 Iminobenzyl antipsychotic
DG01313 Clocapramine
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 34
1 C1x C 15.6608 -20.6997
2 C8y C 14.8216 -19.5807
3 C8y C 15.1713 -18.2519
4 N1y N 16.4301 -17.6924
5 C1x C 17.0595 -20.6997
6 C8y C 17.6890 -18.3218
7 C8y C 17.9687 -19.6506
8 C8x C 14.1222 -17.2728
9 C8y C 12.7934 -17.6924
10 C8x C 12.4437 -19.0212
11 C8x C 13.4928 -20.0003
12 C8x C 19.2276 -20.0702
13 C8x C 20.2766 -19.1611
14 C8x C 19.9969 -17.7623
15 C8x C 18.6681 -17.3427
16 C1b C 16.4301 -16.2937
17 C1b C 17.6190 -15.6642
18 C1b C 18.8779 -16.3636
19 N1y N 20.0668 -15.7342
20 C1x C 21.2557 -16.4335
21 C1x C 22.5146 -15.8041
22 C1z C 22.5146 -14.4054
23 C1x C 21.3257 -13.7060
24 C1x C 20.0668 -14.3354
25 N1y N 23.7035 -13.7759
26 C1x C 24.8924 -14.4753
27 C1x C 26.0814 -13.7759
28 C1x C 26.0814 -12.4471
29 C1x C 24.9624 -11.6778
30 C1x C 23.7035 -12.3772
31 C5a C 23.8434 -15.7342
32 N1a N 25.0323 -15.1047
33 O5a O 23.8434 -17.1329
34 X Cl 11.7972 -16.7434
BOND 38
1 3 4 1
2 1 5 1
3 4 6 1
4 2 3 1
5 5 7 1
6 1 2 1
7 6 7 1
8 3 8 2
9 8 9 1
10 9 10 2
11 10 11 1
12 2 11 2
13 7 12 2
14 12 13 1
15 13 14 2
16 14 15 1
17 6 15 2
18 4 16 1
19 16 17 1
20 17 18 1
21 18 19 1
22 19 20 1
23 20 21 1
24 21 22 1
25 22 23 1
26 23 24 1
27 19 24 1
28 22 25 1
29 25 26 1
30 26 27 1
31 27 28 1
32 28 29 1
33 29 30 1
34 25 30 1
35 22 31 1
36 31 32 1
37 31 33 2
38 9 34 1
|
|---|
